For patients over 50 years old, CamGP (HR = 0.55, 95% CI: 0.36–0.83) was associated with improved PFS, while TorGP showed a trend toward benefit (HR = 0.71, 95% CI: 0.43–1.20) that did not reach statistical significance.
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Reflecting this progression, the studies reviewed showed a trend toward improved methodology over time ( Fig. 2 ).
Additionally, the MT group showed a significant increase in the expression level of Pgc1α in eWAT, while the FMT group only showed a trend of increase without significant difference ( Figure 3F ).
Prior to fasting, LAT2KO mice showed a trend to have greater muscle mass and lower body fat than WT mice, a pattern that was reinforced following fasting (Figure 3B,C ).
During early differentiation, PRL treatment showed a trend toward an increased percentage of Nestin and Sox2-positive cells at PRL concentration ranging from 2 nM to 20 nM; however, these results were not statistically significant compared to the control group ( Supplementary Figure S5 ).
PBM intervention showed a trend toward increased platform crossings and time in the target quadrant, along with a significant reduction in escape latency.
Stratification by age groups (Q1 < 40 years; 40 ≤ Q2 < 59 years; Q3 ≥ 59 years) showed a trend of enhanced potential association between LAP and depression in the elderly population (Q3 group), although the interaction did not reach statistical significance (P for interaction = 0.068).
Simultaneously, the water absorption rate, acid resistance and alkali resistance showed a trend of initially increasing and then decreasing.
Nonetheless, given that current PAF recurrence in our study showed a trend toward an increased risk of cardiovascular mortality, the true association may be even stronger.
It also showed a trend toward reducing infarction and edema after permanent MCAo in C57BL/6 mice.
Consequently, an increased number of repair techniques in the AVVr was significantly associated with a higher rate of AVV reoperation and showed a trend toward association with persistent or recurrent AVVR and death or transplant.
Repeat revascularization also showed a trend similar to that of spontaneous MI (Table 2 ).
11 Consistently, our longitudinal study showed a trend toward an association between distribution entropy and episodic memory decline, as well as a significant association with semantic memory decline.
However, the influence of stimulation intensity on SynWin performance showed a trend, indicating that higher stimulation intensities could have a negative impact on cognitive performance.
In general, the antimicrobial efficacy of the nanoparticle coatings showed a trend similar to those of nanoparticle suspensions.
In the chitin synthesis metabolic pathway, although the expression of genes related to chitin synthesis was suppressed at 72 h, they generally showed a trend of being induced, such as with Pa UAP-1 and Pa CHS-2.
Paired tumor biopsies from baseline and cycle 3 day 1 showed a trend of increased CD8 T-cell infiltration, especially in responding patients.
The signal regulatory factor JAZ, as a negative regulatory factor in JA signaling, showed a trend of first up-regulation and then down-regulation during the post-infection period.
Ropivacaine showed a trend to increase DUSP9 mRNA in cultured STs and led to elevated protein levels in the STs of ERMF patients.
In the interim analysis, OS, a co-primary end point of this study, showed a trend toward improvement (HR=0.80, 95% CI, 0.57–1.11).
The relationship between ePWV and SMI (Skeletal Muscle Index) showed a trend of decreasing SMI as ePWV increased (P overall <0.001).
It can, however, be observed that the HbA1c levels showed a trend of decreasing over the study period, with the HbA1c values at time point 1 being above the recommended HbA1c value of 7% [ 33 ], while they were within the recommendations at time points 2 and 3.
padi populations showed a trend of spreading from the southern to northern regions of China, gradually becoming the dominant wheat aphid species [ 4 ].
Invasive origin showed a trend toward an impact on survival, though it did not reach statistical significance (HR = 2.939, 95% CI: 0.830–10.41, p = 0.095).
Compared to naringin alone, both the naringin acetate and naringin + acetate treatments showed a trend toward slightly increased abundances of Bacteroides , Fournierella , and Holdemanella —genera implicated in short-chain fatty acid production and metabolic activity.