Barely Significant
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“showed a trend”

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For each of glofitamab, epcoritamab and odronextamab, responders showed a trend towards higher baseline tumor CD8 + T-cell infiltration via a variety of techniques, although nuances appear to be important. 40-42 For instance, a specific increase in an effector-like CD8 + T-cell subset was associated with complete response to glofitamab, as was a naïve phenotype. 42 , 43 Increa
At the endpoint in the BM, however, all mitigating treatments showed a trend toward higher levels of engrafted GFP + cells ( Figure 6 K) and led to a significantly lower percentage of senescent cells within the human graft either in PB over time or in BM-derived HSPCs at the endpoint ( Figures 6 L and 6M) and a consistent trend for higher clonogenic potential upon rechallenging into semisolid medium ( Figure 6 N).
Further subgroup analyses revealed that hydrocortisone use was linked to higher mortality, whereas dexamethasone showed a trend toward a protective effect, although the association was not statistically significant (in-hospital mortality: HR 0.70 [0.41–1.18]; ICU mortality: HR 0.69 [0.37–1.29]).
On the other hand, H3N2-CIV/H9N2-G1H reassortants infected A549 cells showed a trend of increased cytokine and chemokine production as opposed to mock and H3N2-CIV infected cells, despite that production of IFN-β, ISG15, IL-6, IL-8, IP-10 and RANTES induced by the reassortants were consistently lower than that by H9N2-G1H.