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Effects of Ultrasound Time, Power, and Temperature From Figure 1 D, the yield of proanthocyanidins showed a trend of increasing and then decreasing with increasing ultrasound time, and when the ultrasound time exceeded 30 min, the yield of proanthocyanidins instead began to decrease, which was attributed to the fact that excessive prolongation of the ultrasound time triggered the oxidation or degradation of proanthocyanidins [ 19 ].
65 Furthermore, correlation analysis between EZH2 expression level and leukemia cell dependency of 22 human AML cell lines without −7 using DepMap portal showed a trend toward a higher vulnerability to EZH2 knockdown in EZH2 low‐expressor cells as reflected by positive correlation coefficient, albeit statistically insignificant due to small data sample size (Supporting Information S1: Figure 6G ). 66 Therefore, whether EZH2 low‐expressing human MDS/AML cells, including those with EZH2 haploinsufficiency by −7, show a higher vulnerability to pharmacological EZH2 inhibition compared to EZH2 high‐expressors with diploid chromosome 7 should be further investigated based on a larger number of human MDS/AML cell lines and patient samples.
The vaginal hysterectomy group also showed a trend toward fewer infective (5.2% vs. 13.0%, 12.8%), wound (1.3% vs. 8.9%, 8.9%) and medical (3.9% vs. 7.3%, 6.9%) complications compared to the abdominal hysterectomy and ovarian surgery groups (Figures 2 and 3 ; Figure S3 ; Tables S6–S9 ). 3.4 By kidney replacement therapy modality Mortality varied by KRT modality ( P = 0.026), peaking at 6.9% among patients on PD compared with 0.6% on HD, 3.3% on HHD, and 0.5% among transplant recipients.
Furthermore, over the course of the maintenance phase (W10 versus W2), the Observed and Chao1 alpha-diversity indices (richness) showed a trend of decrease in both groups, while the Shannon and Inv-Simpson indices (evenness) significantly decreased in the control group (Fig. 4 F and Supplementary Table S14), but the intergroup difference was not significant.