Barely Significant
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“showed a trend”

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Although patients receiving lipid-lowering treatment showed a trend of improved survival rates ( Supplementary Table S2 ), this association did not reach statistical significance after adjusting for other covariates (Model 1: HR = 0.61 (95% CI: 0.37–1.01), Model 2: HR = 0.65 (95% CI: 0.38–1.10), Model 3: HR = 0.65 (95% CI: 0.38–1.10), Supplementary Tables S3 – S5 ).
For the regulate > view contrast, both patients with MDD and HC showed a trend toward higher amygdala activation compared to patients with FMS (T = 3.00, P FWE = 0.055 and T = 2.78, P FWE = 0.093, respectively, all P -values FWE-corrected for voxels in the bilateral amygdala using the AAL3 atlas). 71 No other group comparisons revealed any differences, and we found no evidence that any group exhibited higher amygdala activation during regulate compared to view at baseline.
Kaplan-Meier analysis also showed a trend between increased survival and higher HS AT staining, with a significant difference between patients exhibiting high staining or low staining (median survival 23.5 months [95% CI, 18.8–28.2] for low AT staining [average score <1] and 34.3 months [29.8–38.8] for high AT staining [average score ≥1]; log-rank test P = 0.002) ( Figure 5, D and E ).