“showed a trend”

However, 3 days after 5-FU wash out, aged organoids showed a trend towards an increase in apoptosis (Fig. 3f ), in line with the morphology analysis (Fig. 3b,c ).

Other inflammatory genes such as Tnf, Il6, Il10, Cxcl2 and Ifnb also showed a trend towards higher expression levels in the lungs of RPC mice at this time point.

Samples from 3 young (29–48 years) and 6 old (69–87 years) donors showed a trend for poorer fusion of myoblasts from older (33.7%) compared to younger (56.7%) adults (Fulle et al. 2005 ).

We found that the PNS group showed a trend toward lower incidence rates of HAEC and total complications across all subgroups.

In the CD62L low Th7R subset, the high group showed a trend toward better PFS and OS (Supplementary Fig. 5 ).

Tuvusertib upregulates the death receptor TRAIL-R2, immune checkpoint ligand PD-L1, and NKG2D ligand ULBP-1 in DU145 cells Gene expression analysis of tuvusertib-exposed DU145 and 22RV1 cells showed a trend toward increased expression of immune checkpoint ligands, increased antigen processing machinery, and decreased expression of immunosuppressive factors (Fig. 2 A,B).

Susceptible mice showed a trend of reduced GSK3β phosphorylation, which was significantly restored by agomelatine, indicating normalization of GSK3β activity via inhibitory phosphorylation independent of total protein levels.

Results Finite element analysis and prediction based on specific models: In fractures of the same type, the range of motion (ROM) in all directions of 4 pedicle screw mono-segment fixation showed a trend of higher values compared with 6 pedicle screw short-segment fixation, while the von Mises stress of adjacent intervertebral discs and adjacent facet joints showed a trend of lower values compared with 6-screw short-segment fixation.

In age-stratified analyses, both the 45–60 years group (HR = 1.58, P = 0.078) and the 30–45 years group (HR = 1.89, P = 0.179) showed a trend toward increased risk, but the interaction was not statistically different ( P -interaction = 0.270).

As the Reference group, assessed using the MoCA, showed a trend towards poorer cognitive performance over time, it is possible that similar changes in the Dance group may not have been fully captured due to the limitations mentioned above of the MMSE.

Further, the expression of Mthfd2 and Decr1 at different stages of Fibroblasts showed a trend of inverted “U” shape.

For instance, the relative abundance of Hymenoscyphus , Didymella, Sclerotinia , and Dioszegia showed a trend of decrease from sapling to upper light canopy, while Aureobasidium and the unknown ascomycete showed an opposite tendency ( Figure 1B ).

Consistent with this, our diagnostic staging data ( Supplementary Table S1 ), which showed a trend towards earlier-stage diagnosis, suggested that the screening program contributed to mortality reduction primarily by enabling earlier treatment.

In this study, during the 0–4 M cold-storage, pears showed a trend of continued ripening, indicating that the continued ripening of pears during cold-storage was not long-lasting.

When the treatment was switched back to osimertinib, the patient's clinical symptoms improved rapidly, and head contrast-enhanced MRI showed a trend toward resolution of the brain metastases ( Fig. 2 ).

As is shown in Figure 8 , AKP, ALT and AST all showed a trend of first increasing and then decreasing, the peaks all appeared at 3 h, and the three indexes were respectively 4.87-fold, 4.66-fold and 3.41-fold higher than the H0.

As depicted in Figure H and I, while ICA showed a trend toward amelioration of liver function impairment caused by HFD, this was not statistically significant.

In contrast, the mPFC treated with iMGL‐EV showed a trend toward increased PSD‐95 immunoreactivity that did not reach statistical significance compared to the AD‐Vehicle group. 3.4 hNSC ‐ and iMGL ‐Derived EVs Decrease Proinflammatory Glial Responses in AD Brain The recruitment and activation of microglia and astrocytes in the AD results in a positive feedback loop that leads to a chronically neurotoxic microenvironment (Kim et al. 2018 ).

Environmental conditions such as neutral to low alkaline pH, elevated dissolved oxygen levels, and warmer water temperatures showed a trend of association with increased ETEC prevalence.

At year one follow‐up Fastball showed moderate to good test‐retest reliability in healthy older adult controls, and the six MCI‐dementia converters showed a trend for lower Fastball responses at baseline which will be confirmed with further longitudinal assessment.

ICU‐Cv showed a trend toward lower MOCA scores than HC, but differences were not significant.

Cuban (OR=2.30; 95% CI: 0.73–7.28) and Central American (OR=1.89; 95%CI: 0.45–7.93) participants showed a pattern of greater willingness compared to NHW, while Dominican (OR=0.60; 95% CI: 0.14–2.47) and Mexican participants (OR=0.78; 95%CI: 0.33–1.82) showed a trend toward lower willingness.

Additionally, alcohol consumption showed a trend toward higher hydrocephalus risk, although the result was not statistically significant (OR: 9.755, 95% CI: 0.806–118.013, P = .073). 4.

These analyses showed a trend toward increased LAMP2A protein with age in male skeletal muscles but not in females (Extended Data Fig. 9h ).

As shown in Figures 2B–E , compared with the NC group, serum TC levels were elevated in the HFD group ( P <0.05), TG levels showed a trend toward elevation but were not statistically significant, and HDL-c levels were significantly reduced ( P <0.01), decreasing by approximately 65%.