There was a chance imbalance in baseline imaging characteristics: patients subsequently treated with ARG-007 showed a trend for larger baseline ischemic cores and more severe ischemic injury (greater net-water-uptake) prior to randomisation.
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No factors were significantly associated to inadequate anticoagulation management in univariate and multivariate analyses, although peripheral artery disease (OR 2.02, 95% CI 0.32-21.86, p=0.46) and higher bleeding risk procedures (OR 1.67 per level, 95% CI 0.75-4.28, p=0,21) showed a trend toward increased risk.
Similarly, in this study, IAR showed a trend toward a negative correlation with VRR in RAS-mutated nodules, possibly due to protein denaturation making the ablation zone less absorbable ( 32 ).
Although various cytokines, including IL6, IL1B , and TNF , showed a trend toward upregulation in submerged HNEC, none of these changes were significant (Figure S10 ).
The influence of the K 2 FeO 4 /sludge ratio was relatively weak but still showed a trend of slight improvement with increasing ratio.
Fab′ installation showed a trend toward reduced lung accumulation, possibly due to the decreased cationic charges following Fab′ attachment.
Semiquantitative findings showed a trend for increased low-frequency (delta and theta) and high-frequency (beta and gamma) power, as well as left frontal alpha asymmetry, in depressed patients compared to healthy controls.
Notably, when comparing COPD patients to healthy controls, PILRA expression was significantly downregulated in macrophages, whereas IL1RN showed a trend toward upregulation in dendritic cells, monocytes, and neutrophils.
Consistent with an increased susceptibility to infection, female flies showed a trend toward higher pathogen loads compared to male flies ( Fig. 1d ).
The SOD activity of the bryophytes showed a trend of first increasing and then decreasing with increasing exogenous Cd concentration (Fig. 2 C).
Regarding other clinical strata (such as age, gender, and baseline comorbidities), exploratory Subgroup analysis indicated that elevated ACAG levels showed a trend of being associated with a higher risk of death in most clinical subgroups, with particularly pronounced effects observed in younger patients (≤ 60 years), individuals with higher BMI (≥ 25), males, and patients without specific comorbidities such as AKI, CKD, HF, MI, or COPD.
Notably, mice receiving high-dose SSG showed a trend of body weight loss toward the end of treatment.
Glut2 showed a trend toward increased expression.
TEN was associated with significantly lower risks of infection, multiple organ failure, and mortality, and showed a trend toward reduced need for surgical intervention.
27 Moreover, greater brain BOLD signals has been reported for true memories compared to false ones in the visual occipital regions (BA18 and BA19), as well as in the posterior portion of the hippocampal gyrus (BA36), which also showed a trend-level activation in the present study.
Age was significantly associated with increased experiences of interpersonal conflict, while Hispanic ethnicity showed a trend toward higher levels of interpersonal conflict, indicating a need for further investigation.
Frontline HSCT showed a trend toward better OS and EFS, but differences weren't statistically significant.
Degree centrality, cluster coefficient and efficiency showed a trend towards higher reliability than between centrality and shortest path length ( Fig 2 ).
In investigating the relationship between platelet parameters and mortality in sepsis, we unexpectedly observed in univariable Cox analysis that Gram-positive and Gram-negative bacterial detection was associated with reduced mortality, whereas other pathogens (including fungi, viruses, and atypical organisms) showed a trend toward increased mortality (HR 1.45, Table 2 ).
Diabetes (OR = 0.43 [0.18–1.03], p = 0.59], and lower LVEF (OR = 1.04 [1.0–1.07], p = 0.054) showed a trend toward persisting LAA thrombosis (Table 2 ).
The quantification of club and basal cells showed a trend towards an increase in IPF-derived cells, which, however, failed to reach significance (Supplemental Fig.
The 0.12 μg/kg dose showed a trend towards higher values between 30 and 48 h of development, but these differences were not statistically significant (Fig. 5 a).
Treatment-naive patients showed a trend toward higher EGFR+ rates (66.7% versus 33.3% in pre-treated cases), emphasising the importance of early molecular testing before therapy initiation.
In ADHD-C, Neuno-Ex and Neuno-In also showed a trend toward enrichment for PLS1− genes, but these associations did not remain significant after full multiple-testing correction (Neuno-In: n = 72, p FDR_ perm = 0.074; Neuno-Ex: n = 94, p FDR_ perm = 0.076) ( Figure 7B ).
Microscopic inspection did not reveal substantial detachment or accumulation of floating cells but showed a trend toward a more rounded morphology following treatment with G418, TLN468, and SRI-41315 (data not shown).