“showed a trend”

Although the unclassified subtype lacks a defined biological identity in current classification systems, our findings suggest that, within this single-center cohort, Unclassified subtype clustered exclusively within the high-risk group and showed a trend toward inferior PFS.

In this study, the result was not significant, although it showed a trend towards improvement in depressive symptoms.

In line with enhancer activation defining cell‐type specific gene expression, this comparison showed a trend toward positive correlation of Ph+B‐ALL‐specific EPIs and the Ph+B‐ALL‐defining transcriptional program (Figure 3F ). 2.4.

Treatment‐naïve patients showed a trend toward better outcomes.

This again yielded a short list that included TRIM26 supporting the robustness of our screen (Figure 5 L), Clinically, high TRIM26 expression associated with shorter disease specific survival in PDAC (HR = 1.75, p = 0.020; Figure 5 M), and showed a trend toward worse overall survival that did not reach statistical significance ( Figure S4 G).

Specifically, subpopulation F1-and-F2-mixture, distinguished by both high hypoxia and immune suppressive genes, showed a trend toward better overall survival compared with other subpopulations.

• Baseline thrombocytopenia and lack of response to bsAb were associated with early death, whereas IVIG use showed a trend toward protection.

For instance, a study using an ovine fetus hypoxia-ischemia model first demonstrated that systemic administration of MSC-EVs significantly improved cerebral electrophysiological function and showed a trend toward protecting myelination, highlighting their direct neuroprotective potential in a large neonatal animal model. 67 Subsequent research has focused on miRNAs carried by MSC-EVs, for example, Xin et al found that MSC-EVs deliver miR-21a-5p to microglia in the injured brain region. miR-21a-5p dri

While FSH levels showed a trend toward recovery in PNX-14-treated groups (ranging from 7.54 ± 0.83 to 9.24 ± 0.72 IU/L), these increases were not statistically significant.

(2024), showed a trend toward infusion in preventing hypotension, but these were limited by significant heterogeneity, a lack of subgroup analyses according to infusion type, and the absence of TSA for testing the conclusiveness of the pooled evidence.[ 9 10 ] In the light of such limitations, the degree of certainty regarding the true superiority of infusion or bolus regimens remains undetermined.

Although our PK-PD analysis showed a trend for an association between C min or AUC and outcomes, further prospective investigations in properly sized cohorts remain warranted to confirm these results.

The aggrecan and collagen 2 of the DHJSD treatment group were significantly better than those of the model group at the same time point, and the in vivo inflammatory factors IL-5, IL-1β, and TNF-α, as well as MMP13 and MMP2, showed a trend contrary to that of the ECM.

Changes in NOR behavior in the aging models Compared to the 6 M group, mice in the 20 M group showed a trend toward reduced frequency and duration of exploring the new and old objects by the nose tip (2 cm away from the object) in traditional behavioral metrics ( Figures 3A , B ), though this was not statistically significant (all q > 0.05 after Benjamini-Hochberg correction).

CSP showed a trend towards being shorter in MS-F patients compared to MS-NF.

Magel2 -null mice showed a trend of Adipoq (encoding adiponectin) downregulation in the eWAT, which was reversed by Rec2-Ex4 treatment.

Although the volume ( Figure 2 E) and cell concentration ( Figure 2 F) at which spinoculation was performed did not lead to changes in the CD4:CD8 (1.5 ± 0.4 and 1.4 ± 0.3, respectively), increasing the spinoculation speed showed a trend toward a higher ratio ( Figure 2 G).

The medium and low-dose groups also showed a trend of improvement, though the effects were less pronounced than in the high-dose group.

It should be noted that although the retroperitoneal tumor group showed a trend of greater blood loss and transfusion volume, and the effect size suggested moderate to large clinical differences, these findings did not reach the traditional statistical significance level due to sample size limitations.

Although total Aβ volume (measured by OC antibody for Aβ fibrils) remained unchanged or showed a trend toward an increase, there was a robust and significant reduction in Thio‐S+ dense‐core plaque volume in both the cortex and subiculum (Figure 3D–G ).

In contrast, psychological distress correlated positively with motoric impulsivity in a stop-signal task, specifically under conditions with a pain-related visual distractor, and high values of a negative mood factor showed a trend toward a correlation with more severe discounting of delayed rewards.

While the LIP group showed a trend toward an increased percentage of fat mass (Fig. 1e, f ), their absolute fat mass did not differ from that of the control (Fig. 1g ).

DLS and NTA measurements showed a trend in diameter increase for the mEVs extracted from the powder after 18 months of storage with respect to unprocessed mEVs.

In multivariable analysis, abnormal chest radiographic findings showed a trend toward association with respiratory support, although this did not reach statistical significance.

T4 had a significantly higher probability to be found in the PORCT than in the PORT group and N+ showed a trend to be more frequent in the PORCT group.

After adjustment for relevant covariates, including age, BMI, gender, ECOG performance status, and disease stage, high basal TSH levels showed a trend toward association with improved therapeutic response, although the associations did not reach statistical significance.