Preliminary studies showed a trend towards weaker response to interferon mono-therapy in the presence of occult HBV.[ 2 , 33 ] However, these were followed by several studies which differed in their views and emphasized a minimal role for occult HBV in occult contamination in response to interferon mono-therapy or its combination with ribavirin.[ 28 , 40 – 43 , 45 ] Due to the differing results obtained in various studies, and the absence of prospective controlled trials, it becomes imperative to perform such trials to clarify the role of occult HBV infection and its impact on anti-HCV treatment.
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While the male Fto Δ/Δ mice remained behind throughout adulthood, the females showed a trend of catching up in weight later on ( Figure 3D ).
Overall RFS and OS also showed a trend toward better prognosis in the NPM1 mut group ( Fig. 1B ).
Glutarylcarnitine also showed a trend of increases in a dose-dependent manner at day 4, although the p values were slightly beyond the significance cutoff of 0.05.
Additionally, cytologic findings showed a trend toward improvement in the tamoxifen group.
However, insomnia showed a trend to increase after RT (Table 4 ).
Z-360 was safe, well tolerated, and showed a trend towards reduced pain in phase Ib/IIa clinical study patients with advanced pancreatic cancer when used in combination with gemcitabine and analgesics, such as opioids [ 6 ].
The SSE-supplemented group also showed a trend towards a lower malondialdehyde-modified-LDL autoantibody titer at 12 weeks from baseline.
However, when limiting analysis to individuals without previous ill-health and with adequate energy intake reports, most of the risks instead showed a trend towards protective effects.
Although no single measure was found to be sufficiently predictive to help target candidates appropriately, the 6 MWT showed a trend to significance.
Nevertheless, cancer genes tend to expand across large genomic regions [30] , and examination of eight genes likely involved in breast cancer through low-penetrance mutations– CASP8 , COX11 , ESR1 , FGFR2 , LSP1 , MAP3K1 , RAD51L1 and TOX3 [2] – [6] , [13] , [14] –showed a trend for larger genomic loci (mean ( ) genomic extension = 211 kilo bases (kb) and standard deviation (σ) = 283 kb; compared to = 66 kb and σ = 128 kb for all annotated genes in the CGEMS GWAS rank).
Low Ecstasy users revealed a trend to the faster Alpha subband, whereas high Ecstasy users showed a trend to lower Alpha subband.
59 Elderly patients treated in the pooled randomised trials showed a trend towards better adjusted outcomes (score on modified Rankin scale 0-2 v 3-6) than those who did nor receive thrombolysis (1.8, 0.73 to 4.3; n=137). 59 Previous studies have shown findings consistent with our results but on small datasets. 20 58 60 61 62 63 64 Despite these points, treatment allocation in our study was not randomised.
It is interesting to note that the SNP tested at the CCR5 locus which is associated with both T1D and CeD, also showed a trend towards association with RA.
Clinical features of Heberden's nodes and joint deformity showed a trend towards significance.
Testing BNI activity in exudates collected from plants of increasing age (21, 28, 35, 50 and 70 days; Experiment 2) showed a trend of decreasing BNI activity in older roots (Table 1 ).
scapularis saliva showed a trend to increase CD86 expression of bone-marrow derived DC stimulated with LPS, while it inhibited IL-12 and TNFα protein expression in culture supernatants [ 32 ].We did not observe changes in IL-10 or TNFα mRNA expression at R. microplus SGE concentrations tested in RAW 264.7 cells.
These results showed a trend that the matching sequences of shrimp and other crustaceans are more similar to proteome sequences of the fruit fly than nematode.
The PP analysis showed a trend of reduced risk of LBW, severe anaemia and premature delivery in the SP3 group, albeit the difference between two and three IPTp-SP did not reach statistical significance.
22 , 31 - 33 Our analysis found that MBC showed a trend toward triple negativity, with less than 10% of ER, PR, and HER2/neu positivity, and the incidence of TNBC in MBC is remarka-bly higher than in IDC.
The results of this experiment comparing the proliferation index of tumors treatment with low-and high-dose Celecoxib showed a trend toward a dose-dependent proliferation inhibition response.
There was no significant effect of these compounds in the γ -secretase assay, although thiorphan showed a trend for an increase in AICD signal.
Of these, only PDK4 showed a trend for differential expression between the EB groups.
Test–retest reliability after excluding housewives, illiterate patients or both, showed a trend similar to the overall migraine patients.
2D ), S14G-HN treated mice showed a trend toward improved recognition, though not reaching statistical significance.