Experiment 2 Although we did not observe a differential effect of increasing and decreasing the rate of positive reinforcement in Experiment 1, the data showed a trend for a larger effect of BOOST in the post-manipulation phase, the condition in which the left hand reward rate was increased.
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Conclusions Only steroid treatment (methylprednisolone) and nutritional therapy (EPA + GLA + antioxidants) showed a trend towards reduced mortality.
Contrary to the results in the present study, Sprague-Dawley rats fed HFD from weaning to 90 days had a reduction in testosterone levels [ 35 ], and male mice fed HFD (for 9 weeks) showed a trend toward reduction in testosterone levels compared to the control group [ 17 ].
For the indomethacin allograft group (but not rosiglitazone), GM-CSF level was also significantly decreased and the expression of IL-12p40, IP-10, RANTES, KC, G-CSF and IL-17 showed a trend of down regulation.
Pathway noncompliance showed a trend towards occurrence out of hours (70% vs. 60.5%).
Preliminary data for TJP expression in duodenum samples showed a trend towards lower expression in the endotoxin-positive sample.
Moreover, and consistently with the tumour re-growth, following cessation of either AZD8055 or GDC-0941 for 5 weeks, the morphology of the tumours from these mice also showed a trend towards progression to diffuse large B-cell lymphoma ( Figure 6C , panels g, f, k and l).
An MA-plot showed a trend whereby X-linked genes which were relatively highly expressed in spermatocytes tended to be over-expressed in Dnmt3L heterozygous males (data not shown).
hMSCs cultured on DM2 also showed a trend for increased IBSP expression over control groups from day 7 through 21. mRNA expression of osteocalcin ( BGLAP ), a common biochemical marker of bone formation, 27 exhibited a significant increase in hMSCs cultured on DM1-coated wells over all other groups at days 3, 7, 15, and 21 (Fig. 3 d).
While this clearly has limitations, six miRNAs showed a trend for a stronger upregulation during white pre-adipocyte differentiation compared with brown pre-adipocytes, while another 6 miRNAs showed a trend for a stronger upregulation during brown pre-adipocyte development (see Figure 1 ).
3 Reanalysis of clinical trial data of alendronate (FIT studies) showed a trend towards an increased risk of serious (though not all) AF events. 4 However, analysis of adverse cardiovascular events in approximately 15,000 postmenopausal women in Phase III clinical trials of risedronate demonstrated no increased risk of AF, classified either as an adverse or serious adverse eve
Notably, high RKIP expression levels showed a trend for favorable overall patient survival, whereas high BRAF expression levels tended to be more frequent in patients with worse overall survival.
The Kaplan-Meier analysis showed a trend toward a greater risk of any event during follow-up ( P for trend = 0.064) when comparing anterior wall involvement with inferior or lateral wall involvement ( Table 2 , Figure 1 ).
The expression levels of both of the phosphorylated and baseline proteins in all of the treated animals, but not in the positive control group, showed a trend toward the normal levels of wild-type animals.
Although diabetics with CCS = 0 showed a trend towards higher prevalence of obstructive CAD among symptom categories, not statistically significant differences between groups were observed.
The three-way interaction showed a trend for the interference effect (incongruent trial standard deviation minus congruent trial standard deviation) to be stronger for biological than nonbiological dot motion for the vertical performed movement only, t (9) = 2.87, p = .018 (corrected α = .0125 for four tests; other comparisons, t [9] < 1.15, p > .281).
However, the larger, randomized DECREASE-HF trial showed a trend toward greater reduction in left ventricular systolic diameter for the group with simultaneous biventricular pacing compared to sequential biventricular pacing [ 44 ], and the single-blinded, randomized RHYTHM-II trial did not find a benefit on functional endpoints of VV optimization compared to simultaneous biventricular pacing [ 45 ].
While cultures treated with both TSH (10 U/l) and LY294002 showed a trend toward diminished adiponectin mRNA levels compared with TSH-treated cultures, this did not reach significance (42·7±6·0%).
HHE showed a trend toward association with higher VL in index partners and a similar non-significant association with higher VL in seroconverters adjusted for age and gender (Table 3 ).
Concordant obstructive cases (FEV1/FVC < 0.70 & <LLN) showed a trend towards more severe airways obstruction than discordant obstructive cases (FEV1/FVC < 0.70 & ≥LLN), see Table 3 . 89.3% of discordant obstructive cases had a FEV1 greater than 70% of its predicted value, and none of the discordant obstructive cases had a FEV1 less than 50% of its predicted value.
Results showed a trend toward a lower incidence of invasive fungal infection, with particular differences in mold infections.
In a study by Cho et al.[ 23 ], ADHD subjects with the T allele (A/T or T/T genotypes) of the -3081 polymorphism showed a trend of higher mean score in response time variability of the CPT than those with the A/A genotype, while no differences were found between genotypes of G1287A polymorphism in the CPT performance measures.
They observed that knowledge brokers along with access to systematic reviews showed a trend towards a positive effect when organizational research culture is perceived as low.
In conclusion, the results from the current study showed that 1) endometrial estrogen receptors, which can be carcinogenic, were present in higher levels with diabetes and that exercise training showed a trend to reverse it; 2) levels of p16, a known tumor suppressor, were decreased with diabetes, but reversed when the diabetic animals exercised; 3) endometrial hyperplasia was noted in 70% of the samples from the sedentary diabetic rats, but not in the exercise trained animals.
Conclusions Despite a small patient population in whom traditional methods of cardiac function only showed a trend toward improvement with stem cell therapy, MRI was able to demonstrate a significant increment in circumferential strain in the apex and mid anterior segments.