A non-compartmental analysis of the data of the first study showed a trend of lower exposure.
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In addition, the size of remaining motor neurons showed a trend toward enlargement in Type III-NRG1-trasnduced mice compared to GFP-transduced mice (Fig. 5f ).
Patients within the DDDR-70 group (with paced and sensed atrioventricular delays of 170 and 150 ms, respectively, in most of the DDDR group patients) showed a trend toward higher mortality and an increased incidence of HF compared with the patients programmed to ventricular backup pacing—the VVI-40 group.
For eccentricities from 11° to 33°, faces, animals and cars showed a trend toward an increasing RRV1 in LOC and LO-2.
Peak CK (1666.5 standard units/l, vs 2096 standard units/l, p = 0.25) and the presence of a previous MI (10 vs 1.7 %, p = 0.15) showed a trend towards a significant difference between the two groups.
Hepatic FAS and SCD1 levels were not significantly different between the groups, whereas CPT-1 and AOX mRNA levels were significantly increased in the GALP group compared with the saline group, and MCAD and FGF-21 showed a trend to increase ( Fig. 2B–G ). mRNA levels of HSL and ATGL in adipose tissue were increased in the GALP-treated group compared with control ( Fig. 2H,I ).
Via ELISA assay we could show that total Aβ40 levels showed a trend to decrease (by about 13 %) in meprin β ko neurons ( n = 6) compared to controls ( n = 6) (Fig. 2d ); however due to the antibody specificity we were unable to detect any endogenous mouse Aβ2-40.
concluded that snoring was prevalent in student population, and male gender showed a trend as an independent predictor for snoring, which is similar to our result.[ 6 ] When we compared our result with the general adult population findings, our result is slightly lower than the prevalence of snoring reported by middle-Eastern studies (52.3% Saudi and 28.7% Jordanian BaHammam et al . and
CO 2 production rates was measured, and the result showed a trend of decline in respiration rates with increase in chemical concentrations, with the exception of 1,7-Phen and B[h]Q (30 days) and 4,7-Phen (Table 3 ).
pylori -negative gastric cancers showed a trend of proximal location, higher frequency of microsatellite instability high (MSI-H) and p53 overexpression, but the differences from H. pylori -positive gastric cancer did not reach to the statistical significance.
Neither we, nor any of the previous studies that also showed a trend towards increased risk of MS with COC use[ 2 , 3 ] addressed this issue.
Whereas women in SIMD1–4 born in 1988 and 1989 showed a trend of increasing attendance with decreasing deprivation, there was no consistent effect of SIMD on attendance from 1990 onwards.
Although only modest differences in prediction performance were observed between the optimal libraries identified at each size considered, our results showed a trend toward diminishing prediction performance for sizes exceeding 500 L-DMRs.
The mean RD in the treated group was less than the untreated group at 7.5 months in both longitudinal studies and showed a trend toward wild-type values; however, these differences were nonsignificant ( Fig. 6 ).
Patients with SUVmax-T ≤ 7.95 or SUVmax-S ≤ 9.60 showed a trend of better RFS, although it was not statistically significant ( P = 0.059 and P = 0.078, respectively).
For primary outcomes, when compared with PR, all interventions, including SMV plus PR (OR 3.55, 95% CI 2.22–5.69, P < 0.001), FDV plus PR (OR 3.61, 95% CI 1.74–7.51, P < 0.001), SOF plus PR (OR 4.41, 95% CI 1.61–12.04, P < 0.001), BEC plus PR (OR 14.64, 95% CI 10.58, 18.70, P < 0.001), DCV plus PR (OR 7.80, 95% CI 1.75–34.83, P < 0.001) and TLV plus PR (OR 3.42, 95% CI 2.03–5.75, P < 0.001), showed significant clinical efficacy for SVR12, except for LDV plus SOF plus PR, which showed a trend that it was associated with decreasing SVR12 (Table 3 ).
In our experiments, down-regulation of three miRNAs miR-3619-5p, miR-637, and miR-324-3p was observed, and two mRNAs RAB11FIP4 and CTSS were up-regulated or at least showed a trend in up-regulation.
An analysis of 238 tissue samples by microarray showed a trend for BRMS1 towards a positive association with the ER [ 40 ].
Quantitation of Ki67 in different skin samples demonstrated an actual majority of suprabasal Ki67-positive nuclei and, despite the limited number of samples, showed a trend toward a decrease of this suprabasal fraction with age ( Figure S3A ).
Although weight loss alone may be insufficient for maintaining skin disease remission in obese patients with psoriasis [ 55 ], some recent intervention trials have demonstrated that treatment with a low-energy diet showed a trend towards significant improvement in PASI scores among overweight or obese patients with psoriasis, and that body weight reduction in psoriatic patients receiving either low-dose cyclosporine or biologics increased the efficacy of these drugs [ 56 , 57 , 58 ].
It also showed a trend suggesting an association between increased bleb height and ptosis, but this did not reach statistical significance.
33 Our study results showed a trend for better success rates in older age; nevertheless, this has not reached a statistical significance.
In healthy individuals, opioid blockade showed a trend toward increased ratings of touch pleasantness, while in chronic pain patients it significantly decreased ratings of touch intensity.
Aphids exposed to low or medium doses also showed a trend of reproducing slightly faster than controls and also decreased in reproduction as control aphids were increasing reproduction, so they reproduced less than aphids in high dose treatments.
Reduced reward sensitivity showed a trend to correlate with damage near nucleus accumbens.