Barely Significant
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showed a trend

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Consistent with our previous results, iPSC-derived SNs with WT FUS showed a trend toward decreased tracing over time, which did not reach statistical significance ( Supplementary Figures S2C,D ). iPSC-derived SNs with P525L FUS-eGFP showed a 5-fold decrease in tracing ( p < 0.05, 2way ANOVA, Sidak post-test for multiple comparisons; Supplementary Figures S2C,D ), consistent with the age-dependent neurodegeneration observed in ALS.
showed a trendp > 0.051.0× alpha
While there was no clear dependence between the measured relaxation time constants and the blood pH, measurements with 25 mM hyperpolarized [1- 13 C]pyruvate containing 26.6 μM OX063 radical showed a trend towards a correlation between blood pH ( r = −0.62, p > 0.05) and the T 2 relaxation time constant.
showed a trendp<0.051.0× alpha
Additionally, a few more channels that showed a trend-level difference (uncorrected p<0.05 but not remaining significant after FDR correction) were located approximately in the bilateral frontopolar ([FP]), dorsolateral ([DL]) and ventrolateral ([VL]) regions (uncorrected p<0.01; [FP] ch 36 (d = 0.83; 95%IC 0.19, 1.43), ch47 (d = 0.93; 95%IC 0.26,1.56
showed a trendp<0.051.0× alpha
In addition, in UC patients, Pseudomonas , Staphylococcus , and Dialister showed a trend of relative abundance changes (p<0.05, BH adjusted-p >0.05) when analyzed for PTPN2 genotypes ( S2 Table ) , while Lactobacillus showed a trend of relative abundance changes (p<0.05, BH adjusted-p >0.05) when analyzed for PTPN22 genotype ( S2 Table ) .
showed a trendp = 0.0501.0× alpha
The risk C-allele in the rs2943641 polymorphism, near the insulin receptor substrate 1 gene ( IRS1 ), showed a trend towards association with increased HOMA-IR (beta = 0.36, SE 0.18, p = 0.050), and the T-allele of the rs4607103 polymorphism, near the ADAM metallopeptidase with thrombospondin type 1 motif 9 gene ( ADAMTS9 ), was associated with postpartum diabetes (OR = 2.12, SE 0.22, p = 0.00055).