Exposure of rats to an SE-producing dose of soman was reported to increase anxiety behavior ( Apland et al., 2014 ; Prager et al., 2014, 2015 ), whereas exposure to sub-SE doses of other OP agents showed a trend toward decreased anxiety behaviors ( Schulz et al., 1990 ; Wright et al., 2010 ) or had no effect ( Nieminen et al., 1991 ; Valvassori et al., 2007 ).
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Compared to controls, those who received the program showed a trend of increased MVPA and perceived self-management capacity after 1 month [ 17 ].
2I), and showed a trend towards a longer time spent immobile in the forced swim test (Supplementary Fig. 2J).
However, the hemodynamic instability may be clinically irrelevant because the postoperative outcomes were comparable between the two groups, while patients in the DEX group showed a trend of more favorable incidence of ICU stay and fewer postoperative medical complications possibly because of attenuated ischemia-reperfusion injury.
Serial profiling in a proportion of patients also showed a trend for developing new mutations particularly in AR and BRCA. 47 Association of ctDNA and CTC profiling with response to therapy In a series of 65 patients with mCRPC initiated on enzalutamide, Wyatt et al . 48 collected serial cfDNA samples at baseline, 12 weeks, and end of treatment.
Although the median age of the subjects in these trials was approximately 60 years, several elderly patients were included in these studies, and subset analysis of PFS showed a trend in favor of EGFR-TKI in the elderly group [ 21 – 23 ].
Total CPP showed a trend towards increasing levels, but this did not reach statistical significance ( p = 0.05).
Patients treated with diltiazem had a lower incidence of stroke (RR 0.80, 95% CI 0.65–0.99) whilst patients on an old treatment strategy showed a trend towards a lower incidence of myocardial infarction (RR 1.16, 95% CI 0.94–1.44).
However, the difference only showed a trend toward statistical significance (0.05< p =0.079<0.1).
Mean ± SD weekly intraindividual variability in the EXACT score showed a trend for reduction over time from 5.47±2.71 at week 1 to 3.66±2.74 at week 12.
Bifidobacterium -treated females showed a trend towards increased motor performance relative to both germ-free and conventionalized females, as demonstrated by increased average latency to fall from the rod over all trials ( Fig 5B ; GF females = 224.7 sec ± 10.97, CONV females = 240.6 sec ± 12.50, BIF females = 263.7 sec ± 6.66).
Rainwater d-excess mostly showed a trend of lowering of values across the latitudes, indicating rainfall evaporation and recycling 8 , 29 , whereas only very few samples showed higher d-excess values (12.5, 29.3 and 47.8‰).
HIV-1-BAL-HSA, a hybrid virus composed of HIV-1-BAL envelope expressed on a lab-adapted NL4-3 background, showed a trend in IFN susceptibility similar to those observed with our NL4-3-derived HIV-1ΔEnv-GFP/VSVG construct ( 22 ).
On the impact of SMA lesions on WM The results indicated that SMA lesions indeed compromised WM and that such a deficit could not be reduced to PS difficulties even though patients showed a trend toward slower PS compared to controls.
DMF treatment improved cognitive function (PASAT) and showed a trend towards improved EDSS of MS patients.
After considering the major frequency bands separately, we also found that low and high frequencies behaved differently: delta (SWA) and theta frequencies showed a trend toward stronger GC from cortex to VM across all states, and this effect became significant during sleep (Fig. 5d ).
Moreover, dihydropyridin‐4‐ones 6 d and 6 f showed a trend similar to that shown by 5 e and 5 f concerning their bioactivity and water solubility.
Differences attributable to APS203 and APS698 did not show statistical significance compared to control IgG but APS203 showed a trend towards a decrease in ADAMTS13 activity (Figure 3 ).
PD-L1 positive tumors showed a trend toward improved median overall survival and there was separation of survival curves between the PD-L1 positive and negative groups at around 1 year, though not statistically significant.
The intervention group also showed a trend toward a lower HDL, but this difference was not statistically significant ( p = 0.059).
We observed that a group of school-age children (mean age 14.8) showed a trend towards improvement in behavior (ABC) and a statistically significant improvement in social responsiveness after 12 weeks of treatment.
Effects on physiological and biochemical parameters During the period of 72 h isolation and sleep deprivation, the heart rate and body temperature of volunteers showed a trend of high in the day and low at night, and the circadian rhythm of systolic and diastolic blood pressure was not obvious.
Discussion In this cross-sectional study of elderly patients with T2DM, we found that circulating levels of novel adipose tissue-derived inflammatory factors showed a trend of significant change according to the severity of systemic atherosclerosis.
[ 10 ], the alcoholics were found to be impaired in a wide range of executive domains, with the exception of the Stroop test which nevertheless showed a trend towards statistically significant differences.
Most of these parameters showed a trend of a gradual change in the course of the 8-day study.