The lower molecular weight ST266 fraction significantly improved optic nerve demyelination, but only showed a trend towards improved retinal ganglion cell survival.
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5-HT showed a trend to decrease in LID animals, especially in cortical regions, hippocampus, hypothalamus, and thalamus, indicated by the blue color on the heatmap ( Fig. 2B ); the difference was, however, not significant.
Following patients during treatment showed a trend of higher discontinuation rate for the Total Face mask (57% vs 40%), which agrees with our observation of faster progress of discomfort with Total Face mask in some subjects.
ratti -infected mice show significantly increased release of this alarmin cytokine, while small intestinal explants showed a trend for elevated IL-33 release, although this did not reach statistical significance ( S1 Fig ).
Evaluation of the DNDC model The modeled results demonstrated that NT system showed a trend with an increase in SOC content compared to CT during the 9 simulated years ( Figure 4 ).
Moderate-intensity exercise training, a non-pharmacological intervention that reduces chronic fatigue in patients with FSHD, 24 also showed a trend for improvement in fatigue of old HSA LR mice but without correction of the molecular or histologic phenotype.
SARS-Cov-2 patients admitted after a stroke showed a trend to be younger and to present a large vascular occlusion requiring endovascular therapy.
The study analysis showed a trend toward improvement of motor scores in incomplete cervical SCI in the absence of any serious adverse effects.
According to the voltage profiles in Figure S13 of the Supporting Information, a short circuit occurred on Li||Li and Li|M‐bph|Li as these configurations showed a trend similar to that in cells configured with Li metals without a separator (green solid line) to intentionally induce short circuit.
Gut microbial diversity, which was estimated using the Shannon (t = 3.375, P = 0.001) and Simpson (t = 2.757, P = 0.008) indices, was significantly lower at ES compared to that at BS; however, Chao1 (t = 1.946, P > 0.05) and Ace (t = 1.898, P > 0.05) indices used to estimate richness showed a trend similar to that of the Shannon and Simpson indices but without statistical significance.
Although not significant, concentrations showed a trend that reflected the direction of nutrient flow through the aquaculture part, where the fish feed entered the system, to the hydroponic part, indicating nutrient uptake by the plants [ 18 , 27 ].
MTX showed a trend to increase the C2M level, whereas the level was unchanged with TCZ.
[ 5 ] (double-blinded RCT) included patients with severe COVID-19 and showed a trend towards faster time to clinical improvement that did not reach statistical significance; however because this trial was stopped early (due to the decline in new cases in China), it may have been underpowered to detect an effect.
Graphical representation of total leukopenia events at week 32 showed a trend toward a greater number of leukopenia events when the number of A repeats was equal or higher than five ( Supplementary Figure S1 ).
For central height restoration as well as for volume restoration Tektona® showed a trend to better results.
The other two enzymes involved (cellulase (endo-ß-1.4-glucanase), cellobiohydrolase) showed a trend into the same direction.
The weighted Unifrac distances between consecutive samplings showed a trend over time, with a downward trajectory for almost all calves (Additional file 3 : Fig.
CentA1 KO mice also showed a trend toward enhanced LTP at 40- to 60-min time point, although this change was not statistically significant ( p = 0.15; Mann–Whitney’s U test).
Assessment of SAPS2 at ICU admission also showed a trend for higher severity in VAP.
Correlation analysis between serum NT-proBNP levels and the AIP degrees of invasion showed a trend but was not significant.
In contrast, in the STAMEDE clinical trial, the surgical group showed a trend of insignificant reduction in eGFR compared with the medical group after 5 years follow-up (− 1.1% in medical group, − 7.7% in gastric bypass group, − 6.2% in sleeve gastrectomy group).
The growth of HCT116 xenograft tumours was somewhat sensitive to dietary serine and glycine restriction (as previously shown 7 ) and also showed a trend to a decrease in mice treated with PH755 (Fig. 7c ), consistent with a previous report showing an effect of PH755 on HCT116 tumour growth 24 .
Moreover, CXCR3 ligands Cxcl9 and Cxcl11 also showed a trend of enhanced mRNA expression in SHP099 treated groups (Supplementary Fig. 8 h,i).
Consistent with decreased expression of fatty acid transporter genes in NT-PGC-1α −/− adipose tissue, inguinal WAT isolated from HFD-fed NT-PGC-1α −/− female mice showed a trend toward lower [ 14 C]-palmitate uptake (Fig. 5 D) and gonadal NT-PGC-1α −/− WAT showed a ~ 30% decrease in [ 14 C]-palmitate uptake compared with WT controls (Fig. 5 E).
Interestingly, cell‐free DNA (cfDNA) concentration in CSF‐in DLBCL patients showed a trend of increase from low to high level CNS‐IPI.