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“showed a trend”

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17 Topically administered bevacizumab, alone or as an adjunct to MMC, after trabeculectomy in rabbit eyes showed a trend towards prolonged bleb survival, even though the results of this study were not statistically significant. 18 Recently, topical bevacizumab (0.25 mg) that was administered 5 times with one-week interval was shown to be useful for the success of trabeculectomy at 6-month follow-up. 19 This study investigates the safety and synergistic effect of topical bevacizumab after trabeculectomy surgery with MMC compared to standard trabeculectomy with MMC.
Among 17 patients classified in G2 (60–89 mL/min/1.73 m 2 ) and 5 patients classified in G3 (30–59 mL/min/1.73 m 2 ), the eGFR value in one patient showed a trend to worsen from 80.5 mL/min/1.73 m 2 to 22.3 mL/min/1.73 m 2 (60 M), while those of the other 21 patients remained stable from 76.7 mL/min/1.73 m 2 (BL) to 67.8 mL/min/1.73 m 2 (60 M) (Fig. 2a and b ).