Barely Significant
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“showed a trend”

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In the literature

The pharmacokinetic parameters terminal half-life (HL λz ), maximum concentration in plasma ( C max ), and the area under the plasma concentration–time curve (AUC) from dosing time extrapolated to infinity (AUC 0- ∞ ) showed a trend of dose-dependence towards the detected constituents cycloastragenol, calycosin, GMV and cimifugin in YPFS , based on the doses administered orally (10, 20 and 40 g/kg; Fig. 4 , Table 5 ).
In contrast to the overall results of the TRICC RCT 39 (which showed a trend toward reduced mortality in patients randomized to the restrictive strategy arm), the subgroup analysis of 257 patients with ischemic heart disease showed a trend toward reduced mortality in the liberal strategy arm. 252 For this reason, the FOCUS RCT 250 enrolled 2600 patients to determine whether subjects with cardiovascular disease or cardiovascular risk factors undergoing surgical repair of hip fracture benefit from a higher (<10 g/dL) vs lower (<8 g/dL) transfusion trigger.
Nine treatment comparisons reported a significant effect of Echinacea compared with placebo, while another showed a trend.
Abstracts
Explore (NY) · 2006 · PMC7128305