Although limited by the small sample size ( n = 20), analysis of the 9p24.1, but not 9p21.3, loss subgroup showed a trend for the prediction of low immune score (9p24.1: β = –0.96, q = 0.10; 9p21.3: β = –0.39, q = 0.41) and CD8 T-cell level (9p24.1: β = –1.00, q = 0.11; 9p21.3: β = –0.35, q = 0.46).
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Still, +/hIC1 female placentas showed a trend to reduced microvessel density compared to the wild-type, although to less extent and not statistically significant.
On day 5, the Pax7 protein expression of the exosome treatment group peaked, whereas Myod expression showed a trend of first decreasing and then increasing.
Participants showed a trend towards decreased hippocampal DBSI restriction fraction (marker or inflammation) following PSIL exposure (linear mixed effects model, main effect of timexdrug; p = 0.08).
A fifth site showed a trend toward improved therapist self-efficacy and therapist behavior change in one provider location.
Indeed, the worm tissue homogenate showed a trend toward increased pyruvate levels and decreased lactate levels, which may relate to the analysis being performed on the homogenate of a population of entire organisms rather than the extracellular environment that is analyzed in standard human clinical blood-based analyses.
Alpha diversity measures showed a trend towards higher diversity values in cats without clinical signs ( S1A Fig ), but this observation was not statistically significant (Wilcoxon Rank Sum; observed species richness, Shannon’s diversity index, and phylogenetic alpha diversity; p > 0.05).
Consistent with this, both C2C12-SKO cells treated with si-Tgf-β3 and dual si-Tgf-β(1+3) siRNAs showed a trend to recovery of the MYH4 protein.
Overall, the kernel density curve of the eight economic regions showed a trend of moving to the right from 2005 to 2019.
66.7%, p = 0.039) and showed a trend of having higher grade tumors and more advanced pathological T stages.
The older group showed a significantly larger incremental change ( P for interaction = 0.017), and female patients showed a trend of larger increment ( P for interaction = 0.058: Figure S2 ).
When a single tree was followed over different seasons, it was observed that with one exception of September 2014, wet-intact CY and PY foliage of red spruce showed a trend towards slightly higher concentrations of total inorganic nutrients than those extracted from dried tissue at all collection times ( Figure 4 ).
One study reported a reduced tryptophan concentration in FGR fetuses (QS = 5, mean (SD) μmol/L: 18.1 (14.8) vs 35.6 (7.3), N = 84, P < .001 (own analysis of supplemental data )), 53 and another study showed a trend toward a reduced tryptophan concentration in selective FGR twins compared to their appropriate-for-gestational-age co-twins (QS = 4, N = 20, no P -value reported). 55 In contrast, a metabolomics study revealed higher tryptophan concentrations in FGR (QS = 5, N = 43, P < .0001) and found that trypt
In the USA, a 6-month aerobic exercise showed a trend of reduced hippocampal atrophy and significantly decreased white matter hyperintensity in comparison to stretching exercise in older adults with mild-to-moderate AD dementia [ 33 ].
Overall, chTERT protein and telomerase activity always showed a trend of significantly higher expression in ALV-J tumor tissues than that in tumor-adjacent and normal tissues.
The Phase I trial of BMP-7 showed a trend to a symptom response for knee OA with a lack of dose-limiting toxicity [ 48 ].
One reason that accounts for the enlarged assay window on changes in cartilage structure is that healthy rats showed a trend for more knee joint cartilage when living in the RCC.
As the blood concentration of the compounds was decreased, the production of IL-1β and TNF-α showed a trend of gradual increase.
The Bacillus -dominant samples showed a trend of clustering in PLS-DA ( Fig. 3A ).
Compounds 30 , 32 , 34 , 36 , 38 , and 40 , all of which had a 5‐OH group, showed a trend towards increasing activity with increasing N ‐hydroxyalkyl chain lengths (Table 2 ).
Group 1 showed a trend of increased expression on Day 1 that subsequently decreased, and seven genes were categorized in this group.
22.56; p = 0.0193, q = 0.0590) The percentage difference between treated and untreated eyes showed a trend for more effect of gene therapy on cone predominant amplitudes (light-adapted and flicker) than for rod predominant amplitudes (dark-adapted), though this was not statistically significantly different (p = 0.8844, two-sample t test).
This analysis revealed that tumors with a higher LINC01198 signature score showed a trend of better response to anti–PD-1 treatment (fig.
Notably, the cumulative survival plot showed a trend for the association between this cluster and a higher ACD incidence, but the effect size did not reach a statistically significant level in the adjusted Cox model.
The pooled estimates for endovascular reintervention (PBA or restenting) showed a trend but no significant difference (reintervention in 30% (3/10) of patients in group 1 and 2 vs 14% (1/7) of patients in group 3 ( p = 0.054)).