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“showed a trend”

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3.4.1 Total cholesterol (TC) The combined random-effect model results showed a trend towards a reduction in total cholesterol (TC) levels among kratom users compared to those with low or no kratom use (MD -0.207 mmol/L; 95% CI: −0.415, 0.002), with minimal evidence of heterogeneity (I 2 = 12.1%, P = 0.33; Figure 2A ).