Excerpts

However, those who were in the highest tertile of the network-specific score showed a marginally significant decreasing association with GC risk (OR = 0.56, 95% CI = 0.32–1.00), and there was a borderline significant linear trend ( p = 0.064) in model II.

We also observed that the non-expression of CD133 showed a trend to worse OS ( p = 0.064) ( Figure 12 a).

The PTR group showed a trend for longer OS (20.5 versus 16.0 months, p = 0.064) but was not related to OS in Cox regression multivariate analysis ( p = 0.220).

Earlier year of surgery did not reach statistical significance on the α = 0.050 level in univariable analysis but showed a trend towards shorter OS ( p = 0.064) and was therefore included in the multivariable analysis.

Under criterion 2, age approached significance ( p = 0.064). 3.2.

Among the genes with the most pronounced up-regulation in both OVCAR-3 and SKOV-3 cells, MX1 gene only showed a trend towards prolonged OS (HR = 0.76, p = 0.064), just like IFI44L (HR = 0.79, p = 0.092).

Although located in the intron region where its function was not obvious, rs7165790 was identified as borderline significant in expression quantitative trait locus (eQTL) relationship with BLM ( p = 0.0644).

The association between this SNP and nausea was marginally significant in the dominant model ( p = 0.0645), but no significant associations were found in the other analyses ( Table 5 ).

These relapses had an effect on mice survival ( Figure 5 C): the cetuximab/rapamycin combination was found to result in longer survival compared to the cetuximab/rapamycin/irradiation (close-to-significant difference: p = 0.0648) and to the cetuximab/irradiation (significant difference: p = 0.0015) regimens. 3.

A similar trend was found in U-251MG; however, TRAM-34′s effect in NSC medium did not quite reach statistical significance (see Figure 9 B,C; p = 0.0649).

The hemorrhage–depth interaction approached significance ( p = 0.065), suggesting attenuation of depth-related PTX risk.

On the other hand, preoperative prealbumin ≥ 275 mg/mL (shown to influence survival up to 7 years [ 32 ] in an independent manner) was also associated with a slight trend (non-significant) toward better survival ( p = 0.065) ( Figure 2 (G2)).

Moreover, in the original eCura system, SM2 or SM3 tumors also were not independent risk factors for lymph node metastasis after non-curative ESD, but had marginal significance ( p = 0.065).

As a result, and as indicated in Figure 1 J, the TRAM-34-mediated depolarization of the membrane potential differed almost significantly (p = 0.065, n = 4 pairwise comparison) between irradiated WT and K Ca 3.1 KO cells ( Figure 1 J).

Accordingly, we reported that patients having a PSA DT ≥ 6 months present a significantly lower number of lesions compared to those having a faster rise in PSA levels after primary treatment; we observed the same trend on a patient-based analysis, although after adjustment for multiple testing, the p -value only approached the level of significance ( p = 0.065).

A trend towards significance was observed with a higher amplitude of N75 in patients with no preoperative VF deficit— p = 0.065 ( Supplementary Material Table S1 ).

A recent meta-analysis examining the association between cannabis use and cancer incidence in the United States showed a trend towards a lower risk of cancer among cannabis users, with an overall risk of 0.90 ( p = 0.065), which became statistically significant (0.86; p < 0.025) after removing the data on testicular cancer, which showed an increased risk [ 142 ].

Despite the numerous associations of SARIFA with a poor prognosis, significant association of SARIFA with colon-cancer-specific survival ( p = 0.008) could be solely demonstrated in group A, whereas group B only exhibited a trend toward significance ( p = 0.065).

On multivariate analysis, treatment with CRT showed a trend toward significance for LRC (HR = 2.23, 95% CI 0.95–5.23, p = 0.065).

However, a nonsignificant trend towards an increased intratumoral TOX count was noted in early-stage sCRC ( p = 0.065, as depicted in Figure 4 D).

After the inclusion of the MDS-CI as a categorical variable (reference group: low-risk) in a model with a dichotomized DIPSS, the MDS-CI high-risk category retained its independent prognostic value (HR 14.64; 95% CI 4.42–48.48; p < 0.001), whereas for the MDS-CI intermediate-risk category, the prognostic impact was only of borderline significance (HR 1.97; 95% CI 0.96–4.03; p = 0.065; see Table 2 ).

High MYC expression showed a trend toward worse survival (HR 2.60, 95% CI 0.94–7.15, p = 0.065).

SHI fell slightly short of significance (HR: 1.49, 95% CI: 0.98–2.28, p = 0.065) in the multivariate analysis.

The association between pT stage and vocal palsy persisted as a nonsignificant trend (OR ≈ 1.55, p = 0.065), suggesting a possible gradient of risk without definitive statistical support.

The location of metastatic lymph nodes was borderline significant ( p = 0.065).