Excerpts

Number and relative proportion of leukocyte subsets Mixed linear model analysis revealed no effect of treatment (P > 0.05) on either the absolute numbers ( Table 1 ) or the relative proportions ( Supplementary Table 2 ) of leukocyte subsets in the blood of 35-day-old broiler chickens treated in ovo with MI on ED 17, except a statistical trend in the number of CD4 + cells (P = 0.069).

Regarding immune cells, the density of CD8 + T cells tended to be lower cancer tissues than in paracancerous tissues, with borderline significance ( Figure 2E , P = 0.069).

However, there was a trend toward significance for KIR2DL2 inhibitory receptor in relapse patients (13 relapse patients out of 16 are positive for KIR2DL2) when compared to non-relapse group ( p = 0.069) with a hazard ratio of 3.2 (95% CI: 0.91–11.26) (Table S3 in Supplementary Material).

The concentrations of growth factor, FGF-2 and cytokines IL-4, IL-5, IL-15 and TNF-α were also found to be significantly higher ( p < 0.05 or close to significance, p = 0.0699, for IL-17A) after vaccination in the adult group.

The transcript levels of tnnt2 showed a trend of upregulation in GS2 compared with GS0 individuals (p=0.07).

As expected, a higher number of DSA had borderline significance with a higher number of HLA mismatches ( p -value = 0.07, HLA antigen data).

The kinetic of CBT adaptation to exercise (first minutes of the 6MWT) showed a trend towards higher values of τCBT in PwMS (101 ± 49 s) than in HS (71 ± 14 s; p=0.07), which was however above the limit of statistical significance.

Faecalibacterium showed significant negative correlations with DAS28-CRP (ρ= -0.37, P = 0.044) and a strong trend with DAS28-ESR (ρ=-0.34, P = 0.070).

However, it is notable that in a sensitivity analysis that excluded one influential case, there was a marginally significant moderating effect of salivary total IgG on the HCMV IgG serum-saliva relation [ b = −0.00, t (82) = −1.84, p = 0.07].

Though modestly significant ( p = 0.07), antibody detection using the microarray platform was associated with higher seroprevalence estimates to Pfs230 (β coefficient 0.31, 95% CI 0.08, 0.55) in comparison to studies using indirect ELISA.

Of note, the expression of STAT3 in M-MDSC of CoV2+ when compared to CoV2- participants approached significance (0.4 ± 0.3 vs 15.9 ± 10.6; p=0.07).

Mice with delayed ERBB2-CAR CIK cell treatment on days +22 and +57 after tumor cell injection experienced significantly improved survival compared to untreated controls ( p < 0.01, Figure 3B ), whereas WT CIK cell-treated mice only showed a trend toward improved survival ( p > 0.07).

It was revealed that in the group of parturient women, the age distribution of seropositive and seronegative women differed—29 (25, 33) years and 27 (25, 32) years, respectively (p = 0.07 borderline significant).

No differences were observed among the groups after 8 weeks of treatment; however, memory Tregs showed a strong trend toward increased activation (HLA-DR + CD194 + ) in the L. johnsonii N6.2 treatment group after the washout period ( p = 0.07) (Table S5 in Supplementary Material).

PLA signal of HA specimens differed from deep DA (p< 0.001), while luminal DA regions only expressed a statistical trend (p=0.07) ( Figure 3H ). 3.5.

Defined by methodology A, B, or C, higher PD-L1 group showed a better prognosis trend although the difference was marginally significant as determined by the log-rank test (p=0.07 as classified by methodology A, p=0.14 as classified by methodology B, p=0.12 as classified by methodology C, Figures 1A–C ).

Neutrophils showed a trend to increase in ELA groups (P < 0.07) ( Figure 10C ).

Meanwhile, budesonide significantly reduced BAL CCL11 showed a trend for reduction of IL-13 ( p = 0.07) and IL-23p19 ( p = 0.05) in the BAL of air exposed, but not O 3 exposed mice (Figure 4 , lower panels ) .

Consistently, both antibodies elevated ADPR production in MM cells, with DARA reaching statistical significance (p = 0.03) and ISA showing a near-significant trend (p = 0.07).

About other miRNAs, miR-30a showed an interesting trend resulting higher in NR vs R (p=0.07); instead, there were no statistically significant differences in miR-21, miR-22, miR-34a, miR-125b, miR-150 and miR-155 expression between two patient groups ( Supplementary Figure S6 ).

While IGHJ4 gene usage was not associated with significant differences in prognosis (p = 0.37; Figure 2D ), patients harboring IGHJ6 gene showed a trend towards inferior five-years RFS (p = 0.07; Figure 2E ).

A significantly larger proportion of total CD4 + and CD4 + T EMRA cells in SAT from diabetics were CD57 + CD69 lo CX 3 CR1 + GPR56 + compared to SAT from non-diabetics ( p = 0.051), and approached significance for CD4 + T EM cells ( p = 0.07) ( Figure 5C ).

II–IV), expression of miR-146a was higher in patients with severe GvHD (grade II–IV) compared to patients with no/mild aGvHD (grade 0–I) ( p = 0.003), while expression of miR-155 showed a trend to higher expression in patients with severe aGvHD (stage II–IV) ( p = 0.07).

Renal disease is a major predictor of damage progression in SLE, and our findings of a near-significant association of IL-18 with organ damage in multivariable analysis ( p = 0.07) are supported by previous findings in a smaller study which reported increased serum IL-18 in SLE patients with organ damage ( 53 ).

Compared with Cluster 1, cluster 3 exhibited significantly higher activity scores for “ferroptosis” (adjusted P = 0.025, δ = −0.29), “lipid peroxidation” (adjusted P = 0.025, δ = −0.28), and “glycerolipid metabolism” (adjusted P = 0.028, δ = −0.26), along with an increasing trend for “fatty acid metabolism” (adjusted P = 0.07, δ = −0.22) ( Figure 3E ).