Excerpts

The number of involved spinal cord segments showed a trend toward significance but did not retain it in the multivariable model (β = 0.10, 95% CI: -0.01-0.21, P = 0.091). 3.4.

For SCFAs, butyrate was significantly associated with extreme high vaccine response (aOR:10.00, 95% CI:1.81-107.2; p=0.025), while propionate was of borderline significance (aOR:1.33, 95% CI: 0.97-1.92; p=0.091) and acetate did not show significant association (aOR:1.01, 95% CI:0.99-1.02; p=0.368).

The high-chimerism group showed a trend toward higher median donor γδ T cell counts ( Figure 2C , p=0.0911), suggesting improved engraftment.

The biochemical pregnancy rate per ET also showed a trend toward being higher in the treated than in the untreated group (11.4%, 4/35 vs. 5.9%, 2/34; p = 0.092), although this trend disappeared in the SET-only analysis (14.8%, 4/27 vs. 6.5%, 2/31; p = 0.402).

Compared with the HC group, the PA group showed lower anti-Hsp60 IgM levels (p = 0.0329) and a decreasing trend in anti-Hsp70 IgM levels (p = 0.0925) ( Figure 2E ).

Results Tumor stage did not differ significantly (P = 0.173), while metastasis stage approached significance (P = 0.093), with a higher proportion of M0 cases in the PD-L1 low group.

The significant difference in CD4+ T cell CCR5 density was lost when CCR5 genotype-matched subgroups were compared; however, a weak trend was maintained ( P =0.093, Supplementary Table 4 ).

The high vinegar intake group showed a trend toward longer PFS: the median PFS was 492 days in patients consuming ≥0.05 g compared with 151 days in those consuming less (P = 0.093) ( Figure 7 ).

S vs DNS ( Figure 2 ) small differences were seen for the SIRS and sepsis S and DNS groups, some of which approached significance/were significant (highlighted in bold); SIRS Day1 [lymphocytes (p = 0.0931), CRP (p = 0.1286)], Day2 (white blood cells (p = 0.0885), neutrophils (p = 0.1206) and basophils (p = 0.033) and Day5 (white blood cells (p = 0.0599), neutrophils (p = 0.0879) and lymphocytes (p = 0.1803).

This increase in average AUC value is significant compared with the immunogenicity score ( p = 0.0135) and a strong trend toward significance is observed when compared to the 7-allele method ( p = 0.0938).

There was a slight trend toward increased NK cell degranulation when MDMs were exposed to UV-irradiated virus compared with uninfected (NT) controls ( P = 0.094, Figure 7 B).

On the other hand, expression of CXCR3 and CCR4 showed a trend towards a decrease in Exp-allo Tr1 cells compared to T conv cells (CXCR3 60.3% ± 25.51 vs 86.30% ± 7.7, p=0.0940 ; CCR4 60.3% ± 9.7 vs 93.2% ± 5.2, p=0.0759 ).

Moreover, the secretion of granzyme B by CD8 + T cells was significantly increased ( P = 0.006, Figure 4E ) and that of IFN-γ showed an increasing trend ( P = 0.094, Figure 4F ) after stimulation of the anti-CD3/CD28, in response to the suppression of PTEN.

Quantifying microglia by this classification scheme we found in the cingulum bundle age-related increases in density that approached significance for both amoeboid [ F (1, 11) = 3.36, R 2 = 0.234, p = 0.0941] and hypertrophic [ F (1, 11) = 2.63, R 2 = 0.193, p = 0.1330] microglia ( Figures 6D,E ).

In pairwise comparisons, the separation between RA-ILD and RA-non-ILD groups showed a trend toward significance but did not reach the conventional threshold (R2 = 0.062, P = 0.095).

The frequency of NK cells showed a decreasing trend (mean (MPN) = 8% vs mean (HC) = 14%; p = 0.095) in MPN patients, but no differences were observed in the frequencies of T cells, B cells, CD3 + /CD56 + cells, or T cell subsets ( Supplemental Figure 4B ).

Contrary to extrafollicular area, a clear trend (p=0.0952) towards increased levels, both as frequency or normalized counts, of IFN-α2 hi cells in SLE compared to control follicles was found ( Figure 1F , Supplementary Figure S2B ), further supporting our transcriptomic findings.

Notably, the number of SAE/patient shows a trend toward significance with more SAE in the treatment group (p=0.096).

By contrast, here we did not detect any significant genetic correlations between platelet parameters and AD risk ( Table 1B ), although PDW variability showed a trend of significance (rg [SE] = -0.088 [0.053]; p=0.096).

AD risk showed no significant correlations, although a negative trend was observed with PDW (rg [SE] =-0.088 [0.053]; p=0.096), in line with previous epidemiological reports.

0% ( p =0.013), and there was a strong trend toward better OS than patients with low S727 TILs H score ( p =0.099).

The Kaplan–Meier curve in Figure 2A only showed a trend towards longer OS (log-rank p = 0.0990) in Fn + patients (78%) compared to Fn − patients (61%).

However, PHEN treatment showed a trend ( p < 0.1) toward reduced TNF-α production compared with VEH-treated arthritic rats (Figure 3 C) and PT treatment significantly inhibited TNF-α release compared with VEH- or TERB-treated arthritic rats ( p < 0.05) (Figure 3 C).

Consistent with a more effective bacterial elimination in cerebellum, animals pre-treated with PEA showed a trend toward lower chemokine levels compared to controls ( P = 0.10, multivariate rank-sum test followed by Holm–Bonferroni correction, Figure 4D ).

Recombinant TLR4 alone had no notable impact, the anti-CD14 antibody suggested a mild trend toward ( p ~ 0.1) inhibition of uptake, whereas recombinant MD-2 inhibited ( p ≤ 0.045) only HAdV-D26 ( Figure S3A ).