Excerpts

Furthermore, we also identified a borderline significant association between MPA and an increased Firmicutes / Bacteroidetes (F/B) ratio ( β = 0.027, p = 0.061). 3.5 Associations with functional pathways After filtering several pathways, a total of 116 pathways were selected to examine their association with MPA and SD _change , respectively.

At T1, despite a positive trend (r = 0.2293), there was no statistical significance ( p = 0.061 ).

To summarize, a few effects were observed—most notably, in the gut wall, for CCL20 ( p = 0.047) and to a lesser extent for IL8 (close to significance - p = 0.061) ( Figure 4D ) where a treatment effect was detected, despite pairwise comparisons failing to reach statistical significance. 4.

Hepatic Lipid Contents, and Gene Expression in the Liver and Intestine Clostridium butyricum treatment had no significant impacts ( P > 0.10) on the contents of total lipid, TC and FFAs in the liver of birds ( Table 4 ), but led to a decreasing trend ( P = 0.062) of TG content with significantly reduced ( P < 0.05) contents of FFAs in the liver.

An observed difference for the estimates of microbial composition is that the hosts had a marginally significant explanation for the functional divergence of gut bacteria ( P = 0.062), revealing different physiological adaptabilities between the two frog species.

The KEGG pathway for biosynthesis of secondary metabolites was upregulated with a high level of significance in the direct, high treatment ( Figures 5 , 7 , p < 0.001; Supplementary Figure 4 ) and was also upregulated with marginal significance in the direct, low treatment ( Supplementary Table 4 , p = 0.0626).

Although the change of high-level gentamicin resistance rate was not statistically significant, it also showed an increasing trend ( P = 0.063), which further reduced the selection of antibiotics in clinical practice.

In the same way, there was also a decrease close to significance of Penicillium relative abundance (6.04 × 10 –3 and 3.09 × 10 –2 , respectively, Mann–Whitney test, p = 0.063).

For the α-diversity of the top five eukaryota phyla, two showed significantly ( P < 0.05) increasing diversity with increasing elevation (SAR_norank and Fungi_unclassified) and one ( Mucoromycota ) showed a marginally significant increase ( P = 0.064) ( Supplementary Figure 4 ).

However, the interaction was only marginally significant ( p = 0.064).

The OLT showed a marginally significant higher preference for the new location in the SG than NG ( F (1,51) = 3.549, p = 0.065; Figure 2B ).

At SJER, bacterial richness exhibited a similar, marginally significant, trend ( p = 0.065).

Biovolumes of green algae increased significantly in the 10 mg·L −1 HP dose compared to the control [Figure 7B ; df = 2, Q (0, 10) = 6.81, p = 0.006], where the 2.5 mg·L −1 dose and the 5 mg·L −1 dose already showed substantial and nearly significant increased compared to the control biovolume [ df = 2, Q (0, 2.5) = 4.24, p = 0.067] and [ df = 2, Q (0, 5) = 4.38, p = 0.058], respectively.

There was a weak trend for bacterial OTU richness being higher in post-1945 sites than pre-1945 sites ( F = 3.50, p = 0.068), although no relationship was seen with any of the other environmental parameters.

The Chao1 index either significantly reduced ( p = 0.048) or showed a strong trend to reduce ( p = 0.068) for skin and nasal microbiota after exposure in swine farm A ( Figure 2A ).

Among SCFAs, acetate showed a modest but significant positive correlation with piglet birth weight ( r = 0.20, p = 0.031), whereas isobutyrate showed a positive association with a significant trend ( r = 0.17, p = 0.068) ( Figure 5B ).

At the genus level, there was an increasing trend in the relative abundances of Blautia ( P = 0.068) and Dorea ( P = 0.041) in the SA and SP groups at 65 days of age, however, unclassified_Clostridiales ( P = 0.037) and SMB53 ( P = 0.041) were decreased ( Figure 2I ) compared with the control and SS groups.

ATX-A content was significantly (F-test; R 2 = −0.43, p < 0.01; Figure 4B ) negatively correlated with growth rate, while ATX-A content exhibited a positive, marginally significant (F-test; R 2 = 0.26, p < 0.07; Figure 4C ) correlation with N 2 fixation rate.

A similar pattern was observed in monoculture plates, however this was only marginally significant ( p = 0.07, Figure 5A ).

In our samples, Simpson indices indicated that alpha diversity increased in the presence of plants, yet with marginal significance ( P = 0.07).

Taxonomic diversity in the vegetated soils was weakly, but consistently, higher compared to bulk soil, and differences in Simpson indices were marginally significant (Mann–Whitney test, P = 0.07, Supplementary Table S1 ).

Although the number of paired annotation samples ( N = 22) is small, OCT4 also showed a trend of predictive value in adjacent normal tissues ( p = 0.07) relative to tumor tissues ( p = 0.31) in survival analysis ( Supplementary Figure 6 ).

When analyzed by RDA, pesticide effects were significant in soils 1 and 2 (genus level: pseudo- F = 4.2, p = 0.002 for soil 1; pseudo- F = 1.3, p = 0.008 for soil 2; species level: pseudo- F = 3.7, p = 0.002 for soil 1; pseudo- F = 1.1, p = 0.004 for soil 2), while soil 3 showed a marginally significant effect at the species level (pseudo- F = 1.0, p = 0.07).

We found positive associations that were significant between vancomycin ARGs and vancomycin usage (IRR 10.25, CI 2.32–49.10, p <0.001) and showed a trend toward significance between carbapenem ARG abundance and carbapenem antimicrobial usage (IRR 1.91, CI 1.01–3.72, p =0.07).

Compared with the control group, the antioxidant enzyme activity in the tissues from gilts in the HMSeBA group was increased, and the concentration of malondialdehyde in the colon had a decreasing trend ( p = 0.07).