Excerpts

There was a slightly significant difference in the vacuolation profile of the prion-vehicle group as compared to the prion-FK506+minocycline group ( Figure 4 C,F).

In this case, an interesting trend was observed, since the consensus level tends to be higher for targets with small and mainly closed binding pockets.

Moreover, obese pre-DM metformin patients showed a trend of increase in triglyceride values compared to pre-DM placebo patients (1.89 ± 0.44 vs. 1.83 ± 0.54 mmol/L), without statistical significance.

The question is whether these subtle changes, although not statistically significant when taking into consideration the whole group of subjects, may be significant for the physiology of a particular patient.

A Student’s t -test (two-tailed, heteroscedastic) was applied, and p -values of <0.05 were considered as statistically significant, while p -values of <0.01 were considered as highly significant.

Comparing the PZQ:PVP PM with the CC, the difference between the dissolution profiles was borderline significant ( f 2 = 49.7).

Results obtained at 0 DPI did not show differences between priming treatments for both the 1-MCP treated and untreated leaves, although a decreasing trend following 1-MCP treatment can be recognized in this respect ( Figure 8 A).

The additional NaCl increased the transcript level of AtHAK5 , which peaked at 6 h (the highest expression level was observed in athkt1;1 ) and then displayed a decreasing trend in both WT and mutants ( Figure 3 C).

For instance, higher levels of p-AMPK/AMPK ratio with a concomitant increase of Pgc-1α gene expression in the offspring from females supplemented with resveratrol compared to the control group were observed, being practically significant in both generations.

Additionally, in several lineages, a clear trend toward increased complexity and satellite monomer length was observed.

In morbidly obese patients, hepatic chemerin mRNA showed a trend to be induced in those probands with a BMI > 40 kg/m 2 [ 58 ].

Conclusions Computational evidence supports a marked trend of hTKFC:2DHA:2ATP, i.e., the complex typical of the DHA kinase activity of hTKFC, towards active-site closure in one of the two sites displayed by the dimeric enzyme.

The analysis of normal modes showed a clear trend of the open conformation of hTKFC to progress towards a less open conformation.

The expression of vascular endothelial growth factor (VEGF) was significantly decreased after combined treatment (8 mM MET + 110 μM CUR) and after MET alone, while CUR alone only showed a trend for reduction.

Accordingly, we selected a set of tests, including three significant indices (central TMH, nasal bulbar redness score, mean redness score) and two marginally significant indices (OSDI and NIKBUT first of TBUT) as clinical monitoring indices. 2.2.

Although central TMH, the nasal bulbar redness score, and the mean redness score reached a significant difference, there was only a marginal trend toward significance in the OSDI score, TBUT, assessable time of TBUT, temporal TMH, temporal limbal bulbar redness score, and assessable area of bulbar redness.

Rats that underwent partial nephrectomy showed an increasing trend of bone formation rate compared with rats from the control group [ 28 ].

Also, with a slight trend for increased levels of PKA-Cα in depressed suicide victims only as compared to healthy controls.

In addition, whereas the intake of processed meat has been shown to significantly increase the risk of colon cancer (RR: 1.23; CI 95%: 1.11–1.35), this association was marginally significant for rectal cancer (RR: 1.08; CI 95%: 1.00–1.18) [ 13 , 14 ].

None of the investigated polymorphisms significantly influenced serum levels of homocysteine, vitamin B12, and folic acid, although marginally significant trends to a higher homocysteine and a lower folic acid were apparent in the T allele carriers (C677T polymorphism) when compared to the C allele homozygotes (13 vs. 10 μmol/L, p = 0.051 and 10.4 vs. 14.7 nmol/L, p = 0.063, respectively). 3.

p < 0.05 was considered significant and p < 0.01 was considered extremely significant. 5.

We found that miR-214-3p first showed an increasing trend and then decreased during proliferation and differentiation ( Figure 2 B,C).

Conversely, under both NaCl and ABA stresses, HpGRF6 showed a trend that was opposite to that of hpo-miR396b , suggesting that HpGRF6 is involved in slat and phytohormone ABA stresses.

In all assays, p values <0.05 and 0.001 were considered statistically significant and highly significant, respectively. 5.

p -values < 0.05 were considered significant, p- values between 0.05 and 0.1 (0.05 < p < 0.1) were considered to show a tendency towards significance [ 47 ].