Barely Significant

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In the same region, a similar observational study conducted approximately in the same era concluded that after a follow-up of 4 years, CTO recanalization not only significantly improved quality of life, in terms of physical activity limitation, frequency of angina and greater treatment satisfaction, but also showed a trend towards better cardiac survival and significant lower risk of MACE compared to that seen in patients with failed procedures [ 38 ].
[ 14 ] found a decreasing trend in all study variables (pain, ankle volume, and ankle ROM) between pre- and post-treatment values, proving that the use of different thermal modalities during the transition from the acute to the chronic phase of injury can be suggested as effective treatment options to reduce pain, improve ROM and manage swelling.
Results: The mean LGN volume (right—100 mm 3 , left—96 mm 3 ) and left lingual gyrus volume (6162 mm 3 ) were significantly lower in RPGR patients in comparison to the control group (129 mm 3 , 125 mm 3 , and 7310 mm 3 , respectively), whilst some brain regions related to other sensory information such as the left isthmus cingulate (3690 mm 3 ) and entorhinal cortex (right—1564 mm 3 , left 1734 mm 3 ) were significantly or almost significantly higher in the RPGR group than in the control group (2682 mm 3 , 960 mm 3 , and 1030 mm 3 , respectively).