Barely Significant

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When categorized into three groups according to the tertile of baseline serum NGAL (NGAL tertiles, 1st: 25.4 to 83.7 ng/mL, 2nd: 83.8 to 143.8 ng/mL, 3rd: 143.9 to 567.9 ng/mL), there was a significant trend toward higher serum NGAL levels with older age, hypertension, diabetes, chronic kidney disease, low ejection fraction, high C-reactive protein, higher contrast volume, multivessel coronary disease, larger number of stents, and longer stent length.
Results of a meta-analysis that included 18 randomized clinical trials (RCTs) with more than 4000 OSA patients on CPAP therapy did not show a significant decrease of cardiovascular event risk compared with the control group but only a nonsignificant trend of lower rate of death and stroke [ 37 ].
There was a clear trend—from the aorto-iliac towards only infrapopliteal segments—in increasing prevalence of diabetes (28.3% vs. 60.0%), heart failure (5.4% vs. 15.8%), renal failure (16.6% vs. 49.5%), polyneuropathy (4.6% vs. 17.9%) and CLTI stage of LEAD (8.6% vs. 74.0%).
Although not significant, a slight trend toward better clinical outcomes was reported in PCL-preserved KA MP-TKA. total knee replacement TKA PCL retain sacrifice medial pivot MP kinematic alignment KA This research received no external funding. pmc-status-qastatus 0 pmc-status-live yes pmc-status-embargo no pmc-status-released yes pmc-pro
At subgroup analysis, these dedicated devices showed a trend towards an even more profound reduced risk of RAO compared to the use of nondedicated devices to achieve hemostasis compressing both ulnar and radial artery simultaneously, although differences between subgroups were not significant ( Figure S13 ).