Barely Significant

Excerpts

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Although the citric acid response pattern and the maximum Ca +2 influx response observed in these three cell types are different, the responsiveness to citric acid stimulus in the form of increased Ca +2 influx was a clear trend displayed by these TRPA1 expressing cell types, unlike the lack of any significant response seen with the hTRPV1 expressing CHO cell line (data not shown).
Importantly, because several previous reports suggest that there may be significant gender differences in the natural history of COPD [8] – [10] and some experimental observations show that the leukocyte transcriptional response to other acute stressors (infection) is different in males and females [11] , we recruited participants stratified by sex.