Excerpts

Although our results showed that the expression of this cytokine was higher at the start of treatment, this elevated expression did not translate into production, which only showed a trend toward being higher than in control individuals.

Only in the Luminal group, a borderline significant difference in AUC between the subtype specific and non-subtype specific predictor was observed (corrected p-value: 0.0709).

The confidence interval for the difference between positive and negative control groups was highly significant ( Figure 4 ).

Because there was no interaction effect and the main effect of predator presence was marginally non-significant, we reran the ANCOVA without the interaction term.

A positive trend was indicated towards LTG.

In our analysis, we did not observe any statistical difference in these aspects, but a favorable trend in LTG was found.

Both of them also observed a significant trend in decrease of plasma ApoE levels from ε2 to ε4 carriers, with ε4/ε4 carriers expressing the lowest ApoE levels in the peripheral.

The Asia monsoon exhibited a decreasing trend ( Figure 9 (b) ) [62] , [63] , as did summer insolation, although winter insolation presented an increasing trend at 25°N ( Figure 9 (c) ) [64] .

Dermatology Life Quality Index (DLQI) showed a trend toward an improvement, the mean score was 2.1 at baseline (range 0–7) and decreased to 1.0 (range 0–3) after cycle 3.

P-values ≤0.05 were considered significant (*), P-values ≤0.01 were considered highly significant (**).

This study shows an increasing trend in the spatiotemporal distribution of DF in the Asia-Pacific region over the study period.

Within the primary analyses, while there were trends of interest, no other pathways were method-wide or nominally significant.

The accumulation of vWF + CXCR4 + cells was not significantly reduced by AMD3100 AMD3100 treatment reduced the total number of CXCR4 + cells and CXCR4 + α-SMA + per vessel in the pulmonary arteries of SuHx animals, but there was only a small trend towards reduced number of CXCR4 + vWF + cells after AMD3100 treatment ( Figure 9A-C ).

No significant association was found between CMV seropositivity and job characteristics (p = 0.271) or number of children<18 years old at home (p = 0.058), although this factor was borderline significant.

Two subsequent intravenous injections of IFNγ, BiPPB-IFNγ or BiPPB-mimIFNγ led to the highly significant reduction in collagen I expression (major extracellular matrix protein) and α-SMA (HSC activation marker) expression.

While such studies are likely to be complex, their impact may be significant.

Meanwhile, forced expression of KLF11 by adenovirus in db/db diabetic mice livers significantly decreases blood glucose levels even in a mild trend.

The χ 2 values of all models showed a highly significant departure from an exact fit, which is not surprising given the large sample size.

Moreover, the fluorescence intensities of the 20 antibodies displayed a clear trend towards differentiating between ALS and control samples ( Figure 1 ).

The Global Health Status showed a highly significant increase after the treatment making it obvious that quality of life improves after the treatment.

The effect of Rab27a on prognosis was only marginally significant in WHO Grade II gliomas in CGGA ( Figure 2A ) but was significant for the WHO Grade II gliomas in the Rembrandt cohort ( Figure 2D ).

At the level of species within orders, however, we found a negative relationship that reached borderline significance: species from smaller orders tended to have a higher mean research effort than species from larger orders (Spearman rho between the number of species per order and the average number of publications per species within each order = −0.354, p = 0.055, Figure 2b ).

Nevertheless, future studies should be conducted to determine whether a significant trend might emerge using longer delays (and perhaps a fully within-subjects design).

Then, we assessed liver cell apoptosis and found an extremely significant increase in TUNEL positive cells in BPA-treated rats at 15 and 21 weeks, which accompanied by a modest increased level of serum ALT observed at 21 weeks.

P-values <0.01 were considered as statistically highly significant (indicated by double symbols: *, # or Δ).