Excerpts

There was a nonsignificant trend for an increased prevalence of the p.Cys282Tyr HFE mutations in patients, whereas the prevalence of the beta-thalassemia trait was significantly higher in patients than in controls, but it represented and exclusion criterium for the control group.

In Malawi, there was a highly significant linear downward trend in death rates between 2000 and 2007, with a mean annual incremental death rate reduction of 0.52 per 1,000 population per year [12] .

This difference is, of course, highly significant ( according to a binomial test).

[19] After accounting for the seasonality in pneumonia case fatality, data from Kilifi demonstrated a non-significant decline in pneumonia mortality post-Hib introduction but no evidence of an overall trend in pneumonia mortality over a 9.25-year period.

While not statistically significant, there is a strong trend toward more even distributions for KIR2DL1 , KIR2DL2L3 ( KIR2DL2 and KIR2DL3 ), KIR2DL4 and KIR3DL1S1 ( KIR3DL1 and KIR3DS1 ), all with normalized deviates of the F statistic ∼(−1).

Regarding the impact of MD-CTA on the time required for obtaining IEC opinion and contract signature, a study showed an encouraging trend towards reduced time spent for activating oncology non-profit studies in Italy.

Due to lack of balance in outcome groups in some datasets, RF showed a trend to preferably classify into the most frequent group.

An additional ANOVA analysis confirmed the highly significant difference of the melanomas ESR signal with “High Breslow’s depth” vs nevi and melanomas “Low Breslow” ( Fig. 4B ).

Multiple regression analyses showed a strong association with preterm status, as MMP-9:TIMP-1 and MMP-9:TIMP-2 ratios were markedly significant higher for the key covariate preterm, while for the key covariate labor only the MMP-9:TIMP-2 ratio was significantly higher.

These analyses showed highly significant correlations between individual tissue swelling and circulating CD5 + and CD8 + lymphocyte subsets (Figure 3), thus supporting the conclusions of experiment #1 on the use of the PHA test as an indicator of acquired T-cell mediated immunocompetence in birds.

Comparison of average of the absolute fold change of gene expression of each of the clusters showed a clear trend of higher fold change for all the clusters with upregulated genes (EU, DU and NEU) and lower fold change for all the clusters with downregulated genes (ED, DD and NED) ( Fig. 2D ).

The echo was highly significant when compared to a surrogate distribution generated by computing ERC for unrelated (i.e., randomly assigned) pairs of stimulus and EEG sequences ( Figure 5 ).

The analysis revealed more than 286 highly significant candidate target genes, falling into various functional groups, of which 51% are expressed in the nervous system.

In particular, a highly significant containment of the virus at the portal of entry was found in vaccinated monkeys as compared to controls, with block of virus dissemination to lymph nodes, the primary site for virus amplification and establishment of the virus reservoir.

After Bonferroni correction for multiple testing, p-values less than 0.0125 were considered nominally significant.

Post-hoc analyses of experimenter effects revealed a highly significant interaction with drug, information, and participant’s sex for behavioral measures in men only.

Wavelet analysis of the tidal range confirms the significance of the 15-day periodicity of the spring-neap cycle, while the 28-day periodicity of the apogee-perigee cycle is at the edge of significance ( Fig. 3E,F ).

Instead, pretreatment with either WM or Gö6976 prevented the increase in JNK2 phosphorylation induced by E 2 17G; although a clear trend towards prevention of JNK1 phosphorylation was also observed, this prevention only achieved statistical significance for Gö6976.

In addition, IL-2, IL-5 and GM-CSF showed a clear trend toward a similar elevation.

There was no decrease in fibrosis in the mutants, but a strong trend suggesting a dramatic increase in fibrosis.

However, multivariate regression analysis only recovered a significant relationship for rivers and a marginally non-significant relationship for highways, whereas the effect of geographic distance was no longer significant (model 5 in Table 2 ).

This could be highly significant because conventional signaling components of death receptors so far have not allowed to explain how cancer cells can have highly different selective sensitivity to apoptosis induced by either CD95L or TRAIL [41] .

A similar effect was observed across multiple hours of a single extended exposure to the testing tank ( Figure 2 ) and these effects were highly significant ( Tables S1 , S2 ).

A single CpG site located in the exon 1F noncanonical nerve growth factor-inducible protein A (NGFI-A) transcription factor was a highly significant predictor of AUC in female subjects.

CT also had a moderately significant indirect influence via the motor factor- one aspect of impulsive personality (−0.02) on the age of the age of heroin onset use, and CT had a slight influence on the motor factor (0.19).