Barely Significant

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Among receptive females there was no relationship between initial body mass and the quality of males visited; however, receptive females that visited high-quality males spent more energy on mate choice, lost more mass, and showed a strong trend towards developing smaller follicles ( Fig 2a–c ).
Approximately 50% of newly identified Myc binding sites by Bio-Myc ChIP-Seq overlap with NMyc targets and the newly identified Myc bound regions show enrichment in motif sequence corresponding to the perfect Myc E-Box with a definitely significant p-value (1E-142) ( Figure 4D ).
Although the data from the four separate TIL lines were not statistically significant due to the different intrinsic apoptosis sensitivities of each line, there was a clear trend towards a decrease in Annexin V + cells in each case with TIL from the 4-1BB REP cultures (IL-2+4-1BB) versus control REP cultures (IL-2) when the post-REP cells were re-plated without IL-2 or with added IL-2 ( Figure 7D ). 4-1BB Co-stimulation during the REP Enhances Responsiveness of MART-1 Specific TIL to Antigen Re-stimulation Previously, we reported that MART-1-specific CD8 + T cells that lose CD28 become hypo-responsive to antigenic re-stimulation by peptide-pulsed DC following the REP.