Distinguishing between these or other molecular mechanisms is a highly significant but challenging problem which solution will enable to predict clinical risk of new or investigational drugs.
Excerpts
The correlation was highly significant for most respiratory function parameters with respect to five of the seven sensors composing the array.
The relationship of the species richness of all species to carbon stocks showed no or only marginally significant patterns, both when all plots and only the agroforest plots were considered ( Figure 2 , Figures S1 , S2 , S3 ).
There was a significant hand×tray interaction along with a significant interaction between group and tray and a marginally significant group×hand×tray interaction.
Pre-miR-223 induced a highly significant 64% increase in cell migration.
Our data indicate a decreasing trend in testes size of L. cinereus found dead at wind turbines from July through October.
The prevalence of suspected hepatitis B was highest among participants aged 20–49 years and showed a trend to a sharp decrease from 20 years to zero years old.
This is a highly significant reduction, as the rate was approximately 9%–12% for a similar age group prior to 1992 [8] and equals a reduction of an estimated 1,577,391 HBsAg carriers and a savings of US$17.8 billion for treatment of HBV infections in Zhejiang Province.
DTI Results When corrected for multiple comparisons at p<.05, permutation analysis revealed highly significant reductions in FA in NF1 patients relative to controls, which were spread broadly across the entire brain ( Figure 3 ).
As expected, its expression, even if with slightly different levels, showed a trend similar to P33 in both WT and AfP33 strains ( Fig. 1D ).
a positive trendgold
A stretch of negative log 2 ratio values is typically representative of copy number deletion, while a positive trend denotes a copy number amplification.
All p-values situated between loose and tight cutoffs were attributed to a Marginal significance class.
Testing the Cambridge Face Memory Test original version (CFMT-original; European-ancestry faces from Boston USA) and a new Cambridge Face Memory Test Chinese (CFMT-Chinese), with European and Asian observers, we report a race-of-face by race-of-observer interaction that was highly significant despite modest sample size and despite observers who had quite high exposure to the other race.
hortulanus had a nearly significant negative Tajima's D (p. = 0.052), Significant and negative values of Tajima's D indicate a greater number of low frequency mutations than would be expected under a neutral model of sequence evolution, suggesting a recent population expansion or selective sweep which could artificially inflate migration estimates.
A smaller trial found highly significant dose-response effects of exercise aerobic exercise compared with a control group on both HAM-D 17 mean difference and number of patients in remission [39] .
4 stickers) approached significance, all p s>.30.
BSO also significantly increased TR activity in FaDu and SCC-25 cells and showed a trend toward increased TR activity in Cal-27 cells ( Figure 1C ).
Recently, we also consistently demonstrated a significant trend for a stepwise increase in the observed/predicted LVM and in the prevalence of inappropriate LVM corresponding to advancement in CKD stages in CKD patients.
We found highly significant associations between the LN status (inguinal/benign vs. enlarged pelvic/malignant) and the SUV max and SUV meanA50 30 min p.i., and their absolute and relative differences ( P <0.0001).
An apparent trend to lowering in prevalence by decade was evident.
Differences were considered statistically significant when P -values were less than 0.05 and highly significant when P -values were less than 0.01 (indicated by * and **, respectively).
In contrast to EEPCs, transplantation of EOCs from the control mice did not influence hepatocyte proliferation or their apoptosis, but RBP-J deficient EOCs showed a trend of increasing proliferation and decreasing apoptosis of hepatocytes ( Figure 6B , Figure S4 ).
Statistical Analysis The software program SPSS 18.00 for Windows was used for the statistical analysis, with p<0.05 being considered statistically significant and p<0.001 being considered statistically highly significant.
Interestingly, at 24 h of reperfusion, even though Y-27632 showed a trend of further decrease in IS (32.72±4.59%) compared with TUDCA at 400 mg/Kg, which, however, did not reach statistical significance ( Fig.
Note that in the cases where the correlation approached significance, it was in fact non-significantly negative.