Barely Significant

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Our study using hourly temperature data in a large international study population corroborates the findings of a Taiwanese study with known hourly temperature data at ICH onset which showed a trend of increased ICH occurrence towards the lower temperature and is also consistent with prior investigations and clinical observation of a peak ICH occurrence in the winter due in part to the trigger effect of low ambient temperature on the risk of ICH onset at particular times of the day [ 2 – 5 , 25 ].
When the ‘not consumers before 2009’ are compared to the ‘always consumers’ group ( Fig 8 ), the relative risks of the ‘always consumers’ are always higher, however, there appears to be an increasing trend from 2011 onwards in the ‘not consumers before 2009’, which is not observed in the ‘always consumers’.