Excerpts

Kaplan-Meier plots of poorly differentiated prostate cancer entities (ranked Gleason 8–10) also showed a trend towards longer recurrence-free patient survival for MB-positive cases [ 18 ].

After adjustment, those from northern Europe were less likely to have a high offer rate than those in Southern Europe (aOR 0.19; 95% CI 0.032–1.09, p = 0.062), although this was marginally statistically significant, possibly due to the small sample size.

After egg-laying and further aging, the amount of lipids again showed a slightly increasing trend.

In bumblebee queens, the composition of intact TG molecules showed highly significant trends in association with overwintering.

R-naproxen pretreatment of Swiss 3T3 cells for 1 h also showed a trend of dose-dependent inhibition of EGF-stimulated Cdc42 activation, which was maximal at 300 μM drug and comparable to treatment with 10 μM of Cdc42 specific inhibitor CID2950007/ML141 ( Fig 2B ).

Correlation of oculomotor staging and the clinical phenotype The highly significant correlation of the neuropsychological scores with the executive oculomotor parameters adds to the idea that these qualities of oculomotor function are closely related to a predominantly prefrontal and frontal cortical deficit as well as its descending pathways.

Similarly, highly significant differences between spring and summer were also confirmed for total cholesterol, glucose and triglycerides.

Additional analysis of our data revealed an increasing trend of AEA and 2-AG levels along the HOMA-IR tertiles in the entire sample ( Fig 2A and 2B ).

In the present study, absence of PAO was a borderline significant predictor for DD.

Table 8 shows that for children aged 1–3 years there was a significant trend for decreased stunting in the quartiles with higher sugar (%EAS) intakes [mean (95%CI) in terms of height-for-age Z score -1.22 (-1.42 - -1.01) in Q1 compared to -0.87 (-1.10–-0.64) in Q4 (p<0.05, Bonferroni multiple comparison test)].

Probably due to this small sample size, we observed a somewhat increased risk for OCD in offspring of parents diagnosed with autism spectrum disorder (IRR = 3.08, 95% CI = 0.96–7.16) that fell just short of significance (see Table 2 ).

We found that no single agent is associated with a significant improvement of survival, although a positive trend towards mortality reduction exists for all the three drugs analysed.

We found in our current BCRL cohort that 23.4% of the patients had adhesive capsulitis, but that the duration of lymphedema was not significantly significant in these cases.

Compared with the I/R group, the group that received anti-ST2 alone did not show significant effects on the serum cTnI (68.1±2.4 pg/ml), LDH (1809.1±48.1 U/L) and CK (4387.7±200.3 U/L) levels (all P>0.05), but there was an increasing trend ( Fig 2B and 2C ).

Women with 25OHD inadequacy showed a trend towards a higher likelihood of emergency caesarean section in both unadjusted (Odds Ratio (OR) = 1.32, 95% CI = 0.95, 1.83) and adjusted (OR = 1.39, 95% CI = 0.95, 2.05) models.

This resulted in the detection of a highly significant association of 12 SNPs with the accumulation of anthocyanins induced by PEG ( Fig 4B and S2 Table ).

Estimates of mean school depth between matched schools from both systems were highly significant (R 2 = 0.98, Fig 4 ), as were estimates of school area (R 2 = 0.70, Fig 4 ).

For all analyses, differences at p < 0.01 and p < 0.05 were considered as highly significant and significant, respectively.

There was no consistent modulation of IFN mRNA in the two vaccinated steers euthanized at 48 hpi, whereas there was an overall trend of IFN induction (though not statistically significant) in corresponding samples obtained at 72 hpi ( Fig 2B ).

Additionally, recaptured female biomass was predicted to decrease by about 58% per year at 30m-buffer pools, but tended to increase (i.e., was marginally significant) by about 2.4% per each additional day of mean hydroperiod in all treatments.

showed a trend for a time-dependent increase in BLI signal but this was not significant (One-way ANOVA ( F (3,17) = 1.49), p = 0.25) ( Fig 4C ).

More importantly, no other of these correlations came close to significance.

The drug resistance criteria include no significant decline in β-HCG after 2 therapeutic courses (not exceeding 1/10), stable β-HCG levels or an increasing trend in β-HCG levels.

spicata height ( Table 1 ; Fig 6b ; S1 File ), although average height showed a trend of being highest in canopy microsites, followed by edge and interspace microsites: canopy x ̄ = 28.8 cm ( σ x ̄ = 2.4 ) , edge x ̄ = 27.6 cm ( σ x ̄ = 2.5 ) interspace x ̄ = 22.8 cm (σ x ̄ = 2.3) .

Activation of the anti-apoptotic protein expression by stress and glucocorticoids may be significant for preventing the development of stress-induced psychopathology.