Excerpts

-1562C>T MMP9 polymorphism revealed borderline significance with POAG The prevalence of CC genotype was greater in controls (69.75%) than in cases (61.16%) while frequency of CT genotype was found to be higher in cases (37.94%) as compared to the control group (28.61%).

In a Taiwanese population, highly significant association was observed between PACG and a non synonymous SNP in exon 6 of the MMP9 gene (rs2664538; now merged into rs17576) [ 35 ].

We also found EGFR mutations were more common among elderly patients, and that such patients tended to have worse survival after diagnosis of BM compared to younger patients, with borderline significance (HR = 1.036).

There was a clear trend for a reduced total HES dose in patients with pre-existing renal dysfunction when compared to patients without this diagnosis (7.4 (1.7–17.9) g/kg vs. 12.6 (5.2–19.4) g/kg; p = 0.052).

Conversely, we did not detect a strong trend in locations east of the median line moving eastward, suggesting that the eastern extreme of the corridor has been less dynamic.

Modulation of HMG-CoA and MVA metabolite formation by frataxin knockdown Baseline levels of HMG-CoA (determined by UPLC-HRMS) in sFXN#10 group (117.4 ± 17.2%, Fig 7B ) and sFAN#11 knockdown group (134.3 ± 31.1%, Fig 7B ) showed a trend to higher levels than the si-NC group (100.0 ± 17.3%, Fig 7B ) and in regular HepG2 group (100.4 ± 54.3%, Fig 7B ).

In addition, our result suggested that ITPR2 was a highly significant gene with a P-value of 4.51 × 10 −10 , and it was also detected to be located within a QTL region with a relationship to myristic acid percentage in milk.

Using this test, we found six significantly different correlations and four more marginally significant different correlations that all indicated differences in favor of the GEB.

In our study XO inhibitor use was rather associated with a rather higher risk of sarcopenia with marginal significance, However, this was only demonstrated in a model adjusted for covariates including DM ( S5 Table , model 15) and the magnitude of association was quite small.

440 plosone PLoS ONE PLoS One PLOS PMC5814046 5814046 5814046 29447278 10.1371/journal.pone.0193052 An increasing trend of rural infections of human influenza A (H7N9) from 2013 to 2017: A retrospective analysis of patient exposure histories in Zhejiang province, China Chen Enfu Conceptualization, Funding acquisition, Project administration 1 # Wang Maggie H Conceptualization, Supervision, Writing – review & editing

For the first time in the Asian cohort, a significant trend was found between bilirubin tertiles and CVD/CHD mortality.

Within the nine sncRNAs measured in the validation phase, we observed an overall trend of increased expression in the pSS patients from clusters 1 and 2 compared to the patients in cluster 3.

Studies suggest the effects of PRVS may be significant in daily life in healthy non-clinical individuals [ 6 ].

This plot showed a trend of correlation between the calculated binding free energy and bioactivity of these molecules, indicating the defined docking area is likely the binding site for P5779 and active molecules.

As expected from the results with two-legged tasks, one-legged eyes open stance tests also showed highly significant differences to HCs.

Emissions of dimethyl sulfide (H 2 S) are of marginal significance.

The species distribution across coordinates 2 and 3 ( Fig 8B ) shows that Tappanina selmensis and Siphogenerinoides brevispinosa are highly significant in the lower Ypresian.

With regards to the cumulative meta-analysis, wheelchair basketball and wheelchair racing showed a relatively stable VO 2peak over time, whereas wheelchair rugby showed a trend towards an increase in VO 2peak ( S1 Excel file , sheet “MetaCum Output”).

The difference in the RII values between the two microsites was marginally significant ( Table 4 ).

Tree cover positively correlated with writing (P = 0.033), whereas reading (P = 0.082), math (P = 0.080), and mean of all test results (P = 0.050) ( Fig 2A ), were marginally significant ( Table 1 , Model 2).

A P-value of less than 0.05 was defined as statistically significant and P < 0.001 as highly significant.

There were statistically significant interactions between vaccination status and gender for cognitive reflection and need for cognition, with a marginally significant interaction for faith in intuition ( Table 6 ).

CE showed a linear contrast (marginally significant), indicating that small fine-tuning changes occur for CE.

YKL-40 showed a trend toward increase in manifest HD. sCD27 correlated with YKL-40 which in turn was closely associated to all included markers of neurodegeneration.

Interestingly, when comparing breast cancer tissues and blood from breast cancer, we found highly significant difference between the two groups for rs34404564 at genotypic levels, i.e., the heterozygosity AG and homozygosity GG frequency differences.