This shift was highly significant as determined by the Mann-Whitney-Wilcoxon Test ( P <2.2*10 −16 ).
Excerpts
Comparison between the ratings of the general public and veterinarian responses was highly significant (LR = 330.31; df = 6; p < 2.2e -16 ) with veterinarians rating dog breeds as less sensitive overall than the ratings from the general public.
Further, the concordance of miRNA expression (log normalized) of the common miRNAs was also explored by Spearman correlation and showed a highly significant correlation with rho of 0.81, p<2.2x10 -16 ( Fig 4b ).
The structures look similar but the estimate of the covariate coefficient of the agency effect provided opposite significance results for the F-value (MCMC sample size = 4000): highly significant (p < 2.2e -16 ) vs. not significant (p = .405).
By linear regression analysis, the correlation between the two are highly significant (Spearman's rank correlation = 0.83, P-value <2.2×10 −16 ).
Strikingly, PFC Aliceblue and NAc Cadetblue 2 showed a highly significant overlap in their gene content, with 72 overlapping genes ( S2 Table ; p = 2.2 x 10 −16 ).
As with sequence similarity, whereas there is a significant trend for proteins that are among the top 0.5% of co-expressing pairs to share related ligands, (χ 2 = 1.3e3, p < 2.2e-16), pragmatically the effect size is marginal and only 9.3% of the top 15% of co-expressed pairs show any SEA interactions at all ( Fig 1B ).
Overall, the results exhibited a clear trend of the MAS level increasing with increasing simulated resistance (Spearman’s rank correlation ρ = 0.71, and p = 2.2E-16).
For log propodus height, there was no significant difference in the angle of slope between males and females (p = 0.078), but there was a highly significant difference in slope elevation when slope angles were assumed to be equal (p < 2.22 x 10 −16 ) ( Table 2 ), with males having broader log propodus heights than females throughout the size distribution of log carapace lengths ( Fig 5 ).
A Fisher's exact test shows that the association between sampling in China and pattern 1 is highly significant ( p <2.5 ̇10 −16 ).
Oleic acid content showed highly significant differences between the two species ( P ≤ 3.2 × 10 -16 ), yet NaCl had no significant impact on its levels ( P > 0.05) ( Fig 10c ).
Using Pearson’s χ 2 test, we found the difference to be highly significant ( p = 3.4 × 10 −16 ), possibly suggesting a selection against the G/G (CFA5 locus) T/T (FructoCFA3) genotype combination.
Highly significant positive correlations (p<1×10 −15 , Pearson’s correlation) were found between the HG-ST1.0 and HG-Focus microarray values.
A multivariate test of differences between SLE and control subjects based on the first six PCs was highly significant (p < 10 −15 ), as was the test based on only the first PC (p < 10 −15 ).
The differences of the expression distributions between bound and unbound genes for all the transcription factors under study are highly significant (p-value<1e-15).
This showed a highly significant increased risk of MS associated with smoking with no significant statistical heterogeneity (RR 1.48, 95% CI 1.35–1.63, p<10 −15 , heterogeneity: χ 2 = 7.38, p = 0.60; figure 1 ).
The correlation coefficient at 100 ms is 0.67 (n = 95) and is highly significant (p <10 −15 ).
Of 17,566 detected genes, we identified 1,080 highly significant differentially expressed genes upon viral stimulation (p<1.00E −15 , FDR<1.00E −14 ), including various immune function and inflammation-related genes, genes involved in cell signaling, cell regulation and transcription, and genes with unknown function.
The average correlation coefficient was 0.511 (standard deviation 0.113) which is highly significant ( P <10 −15 ) for the average protein length of 217 residues in the PDB set.
This striking decrease is highly significant (P < 10 −15 by the Wilcoxon rank sum test), and more than twice that observed for any other amino acid.
We have to reject the null hypothesis and this result is highly significant ( p < 10 −15 ).
The difference between means of A and B is highly significant ( P -value < 10 −15 ; two-sided Student's t -test).
Indeed, the upstream regulator with the most highly significant association with the ISO-regulated gene cohort was determined through Ingenuity analysis to be CREB (p-value = 2.52E-15; z-score for activation = 4.157), confirming that transcriptome analysis of the cardiac RNA samples detected predicted and experimentally observed responses to ISO stimulation.
Despite the spread attributable to differences in etiology, the association between EES groups appears highly significant, with Fisher’s exact test p—value = 4.4 × 10 −15 .
This was shown by way of a simple one sample t-test, which for control plants indicated the distribution of response ratio across samples was not significantly different to 1 (theoretical mean for a distribution based on plants with no CO 2 response) at p < 0.05, whereas deviation from this limit among test plants was highly significant (p = 4.72e -15 ) ( S4 Fig ).