Searching for the conserved HeLo domains using the HMM also yielded a significant match to a HET-s/LopB domain from Metarhizium anisopliae ARSEF 23 [GI: 322703231, E-value 1.6e-10], as well as marginally significant matches [GI: 310797955, GI: 317157340, GI: 317033349] in several proteins from Glomerella graminicola , Aspergillus oryzae RIB40, and Aspergillus niger CBS 513.88, respectively [corresponding E-values 0.0042, 0.00082, 0.00083].
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This protein was identified in the NR database with marginal significance levels (E< = 0.010 in psiblast iterations).
When the combined VAT area between L3-4 and L5-S1 was used instead of a single level of VAT (992.3±48.7 cm 2 in men and 1469.4±53.7 cm 2 in women, P<0.001), this merged VAT area was associated with MS with a borderline significance ( Table S3 ).
Nonetheless, the GRIN2B genotype showed a trend to significance in relation to verbal memory ( T allele carriers recalling more words), raising the possibility that effects of these genes on cognition may emerge in larger samples sizes.
As a consequence, most of our results are at the edge of significance.
We detected a highly significant genetic differentiation of eastern J. brevifolia populations with respect to the rest of the archipelago.
QTL analysis identifies modifiers of aganglionosis severity in Ednrb sl/sl rats Final results of interval mapping were considered suggestive, significant, or highly significant linkages when the threshold likelihood ratio statistics (LRS) were 9.9, 20.2, and 30.4, respectively.
Overall, we found an increasing trend of publications on HPSR in LMICs, although only 4% were led by authors from low-income countries (LICs).
In support of our findings, the Agricultural Health Study [22] found a borderline significant association between high consumption of the HCAs MelQx and DiMelQx and incident prostate cancer.
a weak trendgold
While we did not detect a statistically significant association for PhIP, there was a weak trend toward increasing risk.
While not significant (p = 0.055), the contrast between low treatments in Expt 2 and 3 showed a trend of lower survivorship in Expt 3 as compared to Expt 2.
The specific parasite growth inhibition associated with sera from mice immunized with the PP8 was the highest, remaining quite significant even with sera diluted 1,000 fold (i.e. diluted one hundred-time more than the PIAG).
Although these N4 B6- Prop1 -/- mice showed a trend towards increased serum ACTH compared to wild type and heterozygote littermates, the difference was not significant.
In this context, the effects of RBM3 on miRNAs involved in neural differentiation may be significant given that the RNA-BP is highly expressed in multiple brain regions during an early postnatal period, and remains especially high in neural progenitor fields in adulthood [27] .
The highly significant difference between activation in regions contralateral vs. ipsilateral to the cued side indicates that this was not the case.
A nearly significant effect of UGT2B7*2 /*2 genotype with DILI was noted.
The p<0.01 and was considered statistically highly significant.
a positive trendgold
Our objective was to determine if a positive trend in camas density was present following the initiation of passive restoration after accounting for key sources of spatial structure; we hypothesized it would be.
a weak trendgold
There was evidence for a weak trend in Zone E with the lower CI = 0 ( Fig. 4a ).
Considering the number of cells measured (n ∼75), these shifts in the FL distributions are statistically highly significant.
The removal of oxygen was low (>0.5% of the ambient) but highly significant, averaging 0.53±0.34 μmol L −1 with a 95% confidence interval of 0.38–0.68 μmol L −1 .
Our data show that sex can have a highly significant difference on incubation time.
Figure 7B shows that there is a significant reduction in the amount of Iba-1 in the hippocampus of J147-treated huAPP/PS1 mice relative to control huAPP/PS1 mice while the reduction of iNOS is not quite statistically significant due to the large mouse to mouse variability with this marker ( Fig. 7C ).
Given that both primary and metastatic tumor CNVs showed highly significant enrichment of these genes, and because gene expression data showed genes in these pathways to be differentially expressed between primary and metastatic tumors, we chose to focus our functional analysis on these pathways.
qRT-PCR data for GTPase RhoA ( Figure 3J ) and phosphatidylinositol 4-kinase ( Figure 3K ) showed a trend similar to that of the array data ( Figure 2A ), where GTPase RhoA showed fewer transcripts at the 4 or 12 h time points, and phosphatidylinositol 4-kinase showed lower mRNA expression at the 12 or 24 h time points in E 2 -treated samples compared to controls ( Figure 3J and 3K ). qRT-PCR also showed a significant increase in phosphatidylinositol 4-kinase transcript numbers at 24 hours of transition in controls compared to E 2 -treated samples ( Figure 3K ).