Barely Significant

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highly significantqualifiedgold
The highly significant proteins were categorised into five groups depending on their functions and association with the pathogenesis of steatosis: (i) apoptosis and autophagy, (ii) energy maintenance, (iii) anti-oxidative stress, (iv) liver injury (e.g. fat deposition) and (v) liver function improvement (e.g. nitrogen waste detoxicfication and folate-binding protein).
At 0.1% of GO-Au, we observed a decreasing trend (even though it was not statistically significant) in degradation of the scaffold, however at 0.25% and 0.5% concentrations of GO-Au, the degradation rate was significantly reduced in a dose dependent manner compared to naïve chitosan scaffold (Fig. 3A ).
highly significantqualifiedgold
Additional genes that are co-expressed with the abovementioned ones in a highly significant fashion, such as MYO3A (myosin IIIA), IL17RB (interleukin 17 receptor B) and UBXN11 (UBX domain protein 11) (please see the complete network visualization described in the “Data Availability” section at the end of this report), and for which scarce information as related to carcinogenesis or HPV infection is available, are also attractive for further studies and as targets for intervention.
We previously showed that YAP was up-regulated in cSCC tissues and cell lines compared to normal controls, and its expression had an increasing trend from normal skin → precancerous lesions of actinic keratosis (AK) → carcinoma in situ (Bowen’s Disease) → well-differentiated cSCC → moderately and poorly differentiated cSCC 12 .