Barely Significant

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highly significantqualifiedgold
Meanwhile, a previous study using blood samples of patients with Graves’ disease reported that a single nucleotide polymorphism within the lymphoid tyrosine phosphatase (LYP), a potent inhibitor of signal transduction and activation of T-cells, had a highly significant association with Graves’ disease compared to healthy controls 10 .
These variants included; Ecotropic Viral Integration Site 5 ( EVI5 ) rs11808092 (OR: 2.04, 95%CI: 1.4–2.9), TNF Receptor Superfamily Member 1 A ( TNFRSF1A ) rs1800693 (OR: 2.01, 95%CI: 1.45–2.75), Lymphocyte Function-Associated Antigen 3 ( CD58 ) rs1414273 (OR: 2.2, 95%CI: 1.5–3.2), and a nominally significant and not clearly robust Methylenetetrahydrofolate Reductase ( MTHFR ) variant rs1801131 (OR: 1.4, 95%CI: 1.02–1.9).