Barely Significant

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In the subgroup with SCD, 25.0% were A+, and 5.3% were A + T+, compared to 14.8% and 3.8% among cognitively normal individuals, respectively suggesting a possible trend toward increased pathological burden in individuals with subjective complaints, although this should be interpreted cautiously due to the small sample size (Figure S4 ).
Indicative significance of grain-size end-member Loess deposits typically contain fine-grained components derived from three primary sources: (1) direct wind transport and deposition, (2) aggregation-based migration or adherence of fine grains to coarser grains 54 , and (3) clay-sized fractions (<2 μm) produced by weathering and pedogenesis 55 .