Excerpts

The changes referred to an overall trend, and further details about the land-use changes between scenarios can be found in previous publications 33 , 34 .

Transethnic meta analysis using MANTRA 21 revealed four marginally significant SNPs (log 10 BF > 5, Table S6 ); however, at this significant level, the association evidence strongly depends on prior assumptions, so the association need further validation.

The incorporation of PLGA in PCPI and PIPI promoted a decreasing trend of the pH value where it lowered down to 6.87 for PCPI and 6.35 for PIPI at day 7.

The NS score demonstrated a negative correlation with the rsFC between the r-PI and r-striatum ( r = -0.511, p = 0.004) and the rsFC between the r-PI and l-AI ( r = -0.447, p = 0.009, nearly significant after Bonferroni correction) ( Fig. 5 ).

Firstly, large-scale drug screening (130 compounds) in >600 human cancer cell lines identified a highly significant association between EWS-FLI1 , the hallmark translocation of Ewing sarcoma, and sensitivity to the olaparib.

However, after knocking down of ILK, EE still showed a trend of enhanced memory, which suggested that ILK might not be the sole factor to mediate the functions of EE.

A clear trend is observed, where the apparent diffusion coefficient depends monotonically on the radius of the chosen area.

Accounting for this effect on adult body size, adult lifespan was related to protein, but not related to carbohydrate concentrations in the larval diet, although there was a borderline significant negative protein × carbohydrate interaction effect ( Table 1c ).

Measured differences were highly significant with a p-value of 1.205 × 10 −6 [Mann-Whitney-U test].

Results At the beginning of the 21 st century, the upper-tropospheric temperature over East Asia has experienced a significant trend reversal.

With the ordinary periodic oscillation, the upper-tropospheric temperature shows a general decreasing trend before the beginning of the 21 st century, and an increasing trend after.

CTNNA1 , was borderline significant ( Fig. 4b ).

Additionally, we observed a strong trend toward a transient increase in CSF muHTT protein in Hu97/18 CSF following striatal injection of the neurotoxin quinolinic acid (QA) ( Fig. 4D ).

In this case, p ( t ) also shows an increasing trend that eventually yields the increase in the entire activity over time both in the empirical and simulated data, Fig. 5a,c .

The difference in the resulting library size, and hence in screening cost, may be small or even negligible (as was in our case), but when the WT bias is very high, the savings due to choosing the better method might be significant.

Therefore, we adjusted for nominally significant eigenvector of principal component 1 using logistic regression in order to control the potential population stratification for further analysis on remained 98 cases and 98 controls.

A gene set of up-regulated DEGs in NOROS showed highly significant association with normal ageing.

A decreasing trend in the point estimations of transmission rate associated with longer follow-up interval was observed across these studies.

In accordance with several previous studies 27 , 28 , 29 , the magnitude of increased expression of the 300 miR-124 target genes following sponge expression was modest but highly significant (fold change 1.06+/− 0.015 SEM, Fig. 4D ).

In particular, samples showed a decreasing trend in the VEGF activity over time, thus confirming an effective VEGF release (see Supplementary Information , Figure S3 ).

All three doses of 14- O -acetylneoline conferred highly significant protection against pilorerection ( Fig. 2c ) and mobility ( Fig. 2d ) compared to the TNBS-only group.

However, we must admit that the percentage of CXCR4 + cells after Ex-4 treatment (20nM) is not very high (18.46 ± 1.33%), although there was an obvious trend toward an increase after Ex-4 incubation.

The expression of Aβ was significantly increased after 4 weeks of exposure to noise, with an increasing trend that persisted up to 7 days after the cessation of exposure ( Fig. 1A,B ).

2a,b ) suggests that a decreasing trend over the next 30 years is possible.

The figure clearly shows a nonlinear relationship between shear stress and strain rate and the slope, which is a rough estimation of the inverse of viscosity, shows a decreasing trend with stress.