Excerpts

Linear models demonstrated a highly significant effect of the strain factor (χ 2 = 483.04, p = 0.001425) on the MTBE tolerance and on the PFOA tolerance (χ 2 = 590.87, p = 4.613 × 10 −10 ) by suggesting a high variability among the strains in response to both POPs tested ( Supplementary Data Set S6 ).

Conversely, in LAVA, the correlations between these traits were only marginally significant and did not survive correction for pairwise testing ( p = 1.43 × 10 −3 , see Figure 3 and Supplementary Table S31 ).

The index SNPs met the Bonferroni corrected significance level for QT duration, but fell just short of significance for PR duration ( P = 1.44E-03).

When these breeds are excluded, the correlation becomes stronger and highly significant (Pearson correlation = −0.859119; P value = 0.001449).

The cervix, characterized by extremely low richness and evenness, differed markedly from neonatal placental samples, which exhibited higher but heterogeneous alpha-diversity; all indices were highly significant in both cohorts (Chao1 p = 0.00145 in LP; p = 0.000923 in TP; Shannon p = 0.00031 in LP and p = 0.000931 in TP) ( Figures 4 , 5 ).

RESULTS Hypothesis 1: Age‐based terms describing older adults are associated with more negative stereotyping compared to role‐based terms across the pandemic As hypothesized, age‐based framing from October 2019 to May 2020 was associated with more negativity as shown by a significant trend ( β = −0.023, p = 0.00148), compared to the trend for familial role‐based framing which did not reach significance ( β = −0.00343, p = 0.532).

In the SM group of patients, this allele is also more prevalent, but the association did not reach statistical significance ( p = 0.001482, Table 2 ).

The analyses indicated that partitioning into the major haplogroups explains 89.04% of the overall mtDNA variability and corresponds to a highly significant fixation index ( p < 0.0015; Table 2 ).

Excluding the more severe forms (nephrotic syndrome and AKI) in G1, reduction of proteinuria remained highly significant (from 1.1 [0.43–1.6] g/g to 0.3 [0.13–0.5] g/g, P = 0.0015) ( Figure 2 ).

8a ), with intact transport averaging only about 20% (22.784 ± 5.493), a highly significant difference ( p = 0.0015, Fig. 8b ).

Statistical analysis showed a highly significant difference in RTL between SA with aneuploid and SA with euploid karyotype (aneuploid: 0.29 ± 0.03 vs euploid: 0.64 ± 0.12, P = 0.0015) (Fig. 3 ).

Case-control analysis by stage revealed no difference in OS in stage I-III patients but a highly significant benefit in OS in the stage IV driver-positive population (HR 0.39, CI 0.18 - 0.61, p=0.0015 [Figure 2C, 2D ]).

However, when the modulation in luminescence signals of the combinatorial groups (CisPac with Trametinib or CQ) were compared among days and with other groups by two-way ANOVA analysis, highly significant differences ( p = 0.0015 and 0.02, respectively) were observed indicating such combinatorial treatments are sufficient to arrest autophagy in short duration.

The Log-rank (Mantel-Cox) test confirmed the highly significant difference in survival distribution between the control and the BP-C3 groups (p=0.0015).

The malposition rate was highly significant in 2D fluoroscopy thoracolumbar ( P = 0.0015) subgroup.

We observe a highly significant difference (p ≤ 0.0015) with the dominant-negative mutations inducing a lesser change in protein stability than the two other groups of mutations.

According to the TukeyHSD test for the bark volume, only the two independent variables ‘reference’ and ‘diameter’ differed in a highly significant ( p = 0.0015) way from one other.

The study, however, was analyzed as originally planned with the primary endpoint achieving a highly significant ( P = 0.0015) outcome.

A highly significant difference in favor of BNO 1016 was evident at the end of treatment ( p = 0.0015).

Upon E2 stimulation, a highly significant decrease of ESR1 expression in all samples was detected, in EMT by 40.3% (* p = 0.0015), euEMT by 35.7% (** p = 0.0085), and ecEMT by 38.2% (** p = 0.0012) (Fig. 4 A).

While no significant differences in progression-free survival (PFS) or specific overall survival (SOS) were found between negative and positive CYCLON expression groups (Supplemental Digital Content, Figure 4A, http://links.lww.com/HS/A164 ), Kaplan-Meier survival analyses showed highly significant differences between CYCLON staining patterns for PFS ( P = 0.0015) and SOS ( P = 0.0033; Figure 1 B).

Treatment with GEO and citral caused a decreasing trend in plasma cholesterol and LDL-C levels in ApoE −/− mice compared with the GC group; moreover, high-dose GEO and citral increased plasma HDL-C levels ( p = 0.0015 and p = 0.0054, respectively).

Statistical comparison using a paired t -test revealed a highly significant difference between the two groups ( p < 0.0015), as illustrated in Figure 1 A.

This differential response was highly significant ( p = 0.0015). 2.6.

Similarly, observed a nominally significant negative association between CMV positivity and CD8+ CD127− Tem cells using %parent ( p = 1.5 × 10 −3 , FDR = 3.5 × 10 −2 ), but not with %total ( p = 0.26, FDR = 0.69) (Fig. 2b ).