Excerpts

The treatment with CsA led to a highly significant decrease of the teratoma frequency in RAG2 −/− and RAG2 −/− γc −/− mice in comparison to the untreated animals ( P = 0.0019, χ 2 test).

The difference between the rank totals of 30.1 (transparent) and 18.9 (opaque) is highly significant, H(1) = 9.606, p = .0019, ω2 = .184.

apparent T m yielded the expected inverse relationship, and a linear regression showed that the correlation was highly significant (non-zero slope, P = 0.0019) ( Fig. 4A ).

In the moderate and high corrected survival categories, regressions were highly significant (moderate: F 1,5 = 35.51, p = 0.0019; high: F = 9.43, p = 0.0078).

In a multivariate logistic regression model, Asian American race and lower educational attainment were associated with significantly lower odds (adjusted OR, 0.42; 95% CI, 0.26-0.69; and adjusted OR, 0.74; 95% CI, 0.56-0.98, respectively) of annual adherence with LCS after adjustment for age, sex, smoking status, and COPD ( e-Table 3 , Table 4 ) The likelihood ratio statistic is 26.20 and is highly significant ( P = .0019), thus refuting the null hypothesis that all coefficients are simultaneously insignificant and supporting that variables included in the model are important determinants of LCS adherence ( Table 4 ).

aureus isolates for all sample types except for biopsies and other samples, for which the p-value did not reach statistical significance after adjustment for multiple testing (i.e. p < 0.0019) (Fig. 1 , lower panel).

Based on address and date of birth, there was marginally significant cross-clustering between cases of lymphoid leukemia (LL) aged 5-14 years and Hodgkin lymphoma (HL) aged 0–14 years ( p = 0.0019).

The downstream mRNA C1 regulated by miR-4685-3p showed an increasing trend in the CHD_KDBS group, which was higher than that in the Normal group ( P = 0.0019).

These results indicate a positive trend in the number of datasets pooled and the number of genes selected in the signatures (Pearson correlation of 0.38 with p = 1.9 e - 3).

3.1.2 Electrical conductivity Regarding this variable, there were highly significant differences for depth (p = 0.0019); the EC values decreased as soil depth increased from 0.25 ± 0.17 dS/m (0–15 cm) to 0.09 ± 0.07 dS/m (15–30 cm).

The patient was subsequently salvaged using high-dose chemotherapy with peripheral blood stem cell rescue. The local control difference is highly significant (P=0.0019) between the group of low-grade tumours and the group of interme- diate- and high-grade tumours.

Highly significant changes in total leukocytes ( P = 0.0019), macrophages ( P < 0.0001), γδ T ( P = 0.0001), αβ 1 T ( P < 0.0001) and αβ 2 T cells ( P < 0.0001) were also observed in growing feathers of non-expressing Brown line control chickens ( Figure 1B ).

This was a highly significant reduction in comparison to the beginning of treatment ( p = 0.0019).

2 ) but remaining at the lower end of the overall copy numbers (0.05–0.2 copies/μl) and showing no significant pattern of eDNA signal accumulation over time except a decreasing trend for nylon, highly influenced by the high initial copy numbers ( p ≤ 0.0019, Fig. 3 ).

The overall effect of R-Se (25 μmol L −1 ) on the relaxation of arteries (measured in the 10.5th minute post administration of R-Se) was highly significant ( p = 0.0019, one-way analysis of variance, Figure 3 D). 2.3.

Pallidum GMV and the major allele C were also correlated but slightly short of significance (left: β = 0.004, p = 1.9 × 10 −3 ; and right: β = 0.003, p = 4.1 × 10 −3 ) in males.

SNPs with p < 0.05 were regarded as nominally significant and SNPs with p < 0.0019 as significant after Bonferroni correction for multiple testing (0.05/number of SNPs × 2 where 2 is the number of independent traits tested i.e.

CIZ1 [ 15 – 20 ], had highly significant difference between the clusters, with lower relative expression correlating to higher risk subtypes and decreased survival ( P = 0.0019) (Fig. 4 b-c , Table 3 ).

A correlation coefficient of 0.875 was obtained between the two staining procedures, with very little optimization, showing that the correlation was highly significant ( p = 0.0019). 4.

In particular, Pcg was significantly elevated in patients with early-stage PD ( p < 0.0001, p adj = 0.0002) and remained nominally significant in drug-naïve patients ( p = 0.0019, p adj = 0.0550), while also showing a positive association with H–Y stage ( p = 0.0128, p adj = 0.0383).

The gain in ridge width was statistically highly significant ( p = 0.0019).

There was also highly significant difference in the occurrence of hearing loss between those three groups (Pearson Chi-square, p = 0.00193).

We then tested the association of target genes belonging to these pathways with PD risk, and identified nine SNPs in USP37 consistently associated with PD susceptibility in three genome-wide association studies (GWAS) datasets (0.46≤OR≤0.63) and highly significant in the meta-dataset (3.36×10 −4 <p<1.94×10 −3 ).

In both cases the changes seen by each device (from 40 to 100 mmHg) were highly significant ( P = 0.001953 for both the NIRO and ISS), indicating once again that both devices clearly demonstrate the ability to detect the changes induced by the release of the hypoxia clamp.

Three SNP in this significantly associated cluster at a distance of 118–121 Kbp from CUBN had significant test statistics (−log 10 ( P -value) = 3.1), while two SNP in CUBN had test statistics that were close to significance (−log 10 ( P -value) = 2.7).