SLCO1B1 locus was nominally significant in the UKBB ( p -value = 1.84e−03) and genome-wide significant in the TC response GWAS for which sample size was larger ( p -value = 1.89E−09, baseline adjusted).
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While the majority of the patients and controls did not smoke, a relatively large proportion (38.5 %) of the smokers, in this study, were patients with SCM, a highly significant finding ( P =0.00188) similar to that previously reported by other groups in Atlanta [ 7 ].
Following this statistical study, the model was highly significant, which was confirmed by the Fisher test of F-model value = 14.89, and 9.172 on 9 and 6 DF, and p-value = 0.001881, and 0.00695 for E 24 , and hydrocarbon degradation, respectively.
borderline significancep = 1.89 × 10 −3
Enrichment in genes expressed in the adrenal gland for TS-ADHD-ASD was also highlighted, reaching borderline significance ( p = 1.89 × 10 −3 , with a significance threshold of p < 1.67 × 10 −3 ) ( Figures S2 and S3 in Supplement 1 ; Table S10 in Supplement 2 ).
The difference between the rank totals of 30.1 (transparent) and 18.9 (opaque) is highly significant, H(1) = 9.606, p = .0019, ω2 = .184.
The downstream mRNA C1 regulated by miR-4685-3p showed an increasing trend in the CHD_KDBS group, which was higher than that in the Normal group ( P = 0.0019).
3.1.2 Electrical conductivity Regarding this variable, there were highly significant differences for depth (p = 0.0019); the EC values decreased as soil depth increased from 0.25 ± 0.17 dS/m (0–15 cm) to 0.09 ± 0.07 dS/m (15–30 cm).
The overall effect of R-Se (25 μmol L −1 ) on the relaxation of arteries (measured in the 10.5th minute post administration of R-Se) was highly significant ( p = 0.0019, one-way analysis of variance, Figure 3 D). 2.3.
Interactions for race-by-year were borderline significant for weekend bedtime ( p = 0.0019) and weekend sleep duration ( p = 0.0064).
Npas4 cKO mice exhibited a highly significant increase in the total number of sequences (Control: 102.1 ± 17.07, n = 14; cKO: 185.1 ± 16.67, p = 0.0019, n = 13, Fig. 4 j), alongside significant increases in the total bout numbers (Control: 20.57 ± 2.5, n = 14; cKO: 28.69 ± 1.58, p = 0.0123, n = 13, Fig. 4 k) and the overall bout span (Control: 1.97 ± 0.39, n = 14; cKO: 3.21 ± 0.41, p = 0.0368, n = 13, Fig. 4 l).
CIZ1 [ 15 – 20 ], had highly significant difference between the clusters, with lower relative expression correlating to higher risk subtypes and decreased survival ( P = 0.0019) (Fig. 4 b-c , Table 3 ).
of borderline significanceP = 0.0019
In regards to the APOL1 region and fluid loss, the association remained below our significance threshold for rare variants (0.00109) in the random effects meta-analysis conducted in the entire population ( P = 0.0008), was of borderline significance in the fixed effects model in the entire population ( P = 0.0019), as well as both models limited to only Caucasians (fixed: P = 0.0013, random: P = 0.002).
a trend towards significancep -values < 0.0019
For all analyses, we report p -values at two thresholds: p -values < 0.01 to denote a trend towards significance, and p -values < 0.0019 to denote statistically significant findings after accounting for multiple testing.
showed a trendp = 0.0019
In addition, the number of days before maximum daily pollen occurrence showed a trend towards earlier pollen release during later years (R 2 = 0.287, p = 0.0019). 3.2.3.
slightly short of significancep = 1.9 × 10 −3
Pallidum GMV and the major allele C were also correlated but slightly short of significance (left: β = 0.004, p = 1.9 × 10 −3 ; and right: β = 0.003, p = 4.1 × 10 −3 ) in males.
did not reach statistical significancep = 0.0019
Other women also had higher rates of positive TBI screen on the BTBIS than White women; however, differences did not reach statistical significance after correction for multiple comparisons (26.4% vs. 15.1%, p = 0.0019).
This ANOVA showed a highly significant main effect of group [ F (2,182) = 6.5, p = 0.0019].
A correlation coefficient of 0.875 was obtained between the two staining procedures, with very little optimization, showing that the correlation was highly significant ( p = 0.0019). 4.
Age, gender, BMI, and 2-year Elixhauser scores were all highly significant risk factors for VTE Not Hispanic, or Latino showed a significant risk of VTE ( p = 0.0019).
Finally, the effect of SFN on miR-181a was evaluated as a major miRNA involved in hematopoiesis. Results The results of this study showed an increasing trend (2.9-fold, P=0.0019) in miR-181a expression levels in AML patients as compared with HCs.
SNPs with p < 0.05 were regarded as nominally significant and SNPs with p < 0.0019 as significant after Bonferroni correction for multiple testing (0.05/number of SNPs × 2 where 2 is the number of independent traits tested i.e.
In a multivariate logistic regression model, Asian American race and lower educational attainment were associated with significantly lower odds (adjusted OR, 0.42; 95% CI, 0.26-0.69; and adjusted OR, 0.74; 95% CI, 0.56-0.98, respectively) of annual adherence with LCS after adjustment for age, sex, smoking status, and COPD ( e-Table 3 , Table 4 ) The likelihood ratio statistic is 26.20 and is highly significant ( P = .0019), thus refuting the null hypothesis that all coefficients are simultaneously insignificant and supporting that variables included in the model are important determinants of LCS adherence ( Table 4 ).
The gain in ridge width was statistically highly significant ( p = 0.0019).
These results indicate a positive trend in the number of datasets pooled and the number of genes selected in the signatures (Pearson correlation of 0.38 with p = 1.9 e - 3).
The treatment with CsA led to a highly significant decrease of the teratoma frequency in RAG2 −/− and RAG2 −/− γc −/− mice in comparison to the untreated animals ( P = 0.0019, χ 2 test).