Excerpts

In contrast, assessment of two contextual parameters within the stroma IM region of tumors, i.e., the number of CD20 cells within 20 μm radii of CD20 and CD4 cells, termed the CD20 Cluster Score , yielded a highly significant association with OS (HR 0.38; p = .003).

There was no effect of group but there was a highly significant interaction between dimension and group [ F (2,34) = 6.83, p = .003].

When added to the multivariate, it was a highly significant predictor of future rural medical practice (OR 2.50 (1.36 to 4.60, p=0.003).

Renal Function Tests The results showed a highly significant increase in creatinine levels in the infected + MTZ-treated group compared to the non-infected non-treated group ( p = 0.003).

Whereas the difference did not reach statistical significance in either population alone, it was significant (P = 0.003) when combined controls of both populations were compared to combined patients of both populations.

Genotype combination analysis for the various miRNA polymorphisms revealed that the DROSHA TC genotype exhibited a highly significant negative association with RIF prevalence when combined with the RAN CT genotype (adjusted odds ratio=0.314; 95% CI, 0.147-0.673; P=0.003; false discovery rate-adjusted P=0.023).

On the log-log scale, the correlations are 0.95 (no correctors) and 0.97 (+ELX/TEZ), and they are highly significant ( p = 0.003 and p = 0.002, respectively).

Moreover, a borderline association was found for respiratory rate as a risk factor for death/intubation (OR for unit increase = 1.07, 95%CI = 1.02–1.17, p = 0.01), while an increase of PaO 2 /FiO 2 had a trend towards significance as a protective factor for the composite outcome (OR for unit increase = 1, 95%CI = 0.98–0.99, p = 0.003).

When the Sham group was compared to the Cont group, a highly significant decrease was seen in this group ( p = 0.003).

An analysis of covariance with adjustment for age and sex suggested an overall trend across quintiles (adjusted mean ‘g’ = 0.02, 0.14, 0.13, −0.09 and −0.18 respectively; p = 0.003).

bifidum was highly significant (Mann-Whitney U, p = 0.003) ( Figure 5(c) ).

Similarly, leptin associations with BMI were highly significant among the runners (r = 0.75, p < 0.003) but not Ache (r = -0.17, p < 0.50).

However, meta-regression of studies arranged by initiation year revealed a significant trend toward a decreased MD with more recent surgeries ( P = 0.003).

In female patients with breast cancer, there was a strong positive relationship and highly significant correlation between HMTV and BRCA1 as well as BRCA2 (r = 0.443, p = 0.003 and r = 0.58, p = 0.006, respectively; p < 0.01).

Presence of YMV and YMMV in Distinct Yam Species The interaction between viral species and yam species was found to be highly significant across the entire country, with a p -value of less than 0.05 ( p = 0.003).

Over the past 65 years, the B IM also showed a negative trend of −0.14 ± 0.04 GtC yr −1 per decade, statistically significant at the 1% level ( P = 0.003), with a positive B IM in the early part of the record and a negative B IM in the most recent years (Extended Data Fig. 1 ).

Comparative analyses of functional connectivity strength within the four regions of interest (ROIs) and among the six ROI pairs in the two athlete groups demonstrated highly significant differences in correlation coefficients for PFC-L ( P = 0.003, Hedges’ g = 1.48, 95% CI[0.74, 2.22]), PFC-R ( P = 0.003, Hedges’ g = 1.49, 95% CI[0.75, 2.23]), M1-R ( P = 0.003, Hedges’ g=−1.34, 95% CI[−2.07, −0.61]), PFC-L-PFC-R ( P = 0.004, Hedges’ g = 1.50, 95% CI[0.76, 2.24]), and M1-R-M1-L ( P = 0.001, Hedges’ g=−1.77, 95% CI[−2.26, −0.98]).

Comparison of Kaplan–Meier curves showed a highly significant negative impact on disease‐free survival ( p = 0.003) and overall survival ( p = 0.006). 3.3.

However, there was a highly significant BET effect ( p = 0.003), which, when coupled with the HS × BET interaction ( p = 0.031), clearly showed that the combination of BET and AOX, but not BET alone, protected against the negative effects of HS on MFI ( Table 5 ).

The SCL‐9 showed a moderately significant correlation with victimisation ( r = 0.28, p = 0.003).

Figure 2 displays a reversed Kaplan–Meier plot, demonstrating a clear trend whereby higher PCL‐R scores were associated with an increased likelihood of conversion to schizophrenia following the FPE (log‐rank test p = 0.003).

2.2 Combining ability effects estimated The analysis of variance for the combining ability ( Table 3 ) revealed that the mean squares of GCA was positive and highly significant for the days to harvest (P < 0.003013), HPW (P < 0.0009951), HSW (P < 0.048880), SYH (P < 0.01811), pod length (P < 1,878e-07), pod width (P < 0.0011664), seed length (P < 0.006127), and seed width (0.04096).

Again, in sharp contrast with this result, highly significant differences have been observed for the TuMV-DV across the four thermal environments ( Fig. 2A , red lines and symbols: χ 2 = 8.7213, 1 df, P = 0.0031).

Looking specifically at line of advanced disease therapy, there was a significant trend to longer PFS ( p = 0.0031 ) and OS ( p = 0.0002 ) for patients receiving nal-IRI + 5-FU/LV in earlier lines of therapy, compared with later (Fig. 2 ).

We observed similar results when performing the enrichment analysis for the Segway segmentation track of GM12878 ( S4 Table ): strong enhancers were the most enriched (p < 0.0001); weak enhancers and active promoters did not achieve significance at the Bonferoni threshold (p = 0.0031 and p = 0.0419, respectively).