Excerpts

After controlling for confounding factors, there was a strong evidence of a decreasing trend in care seeking with increasing distance to care ( P ≤ 0.005).

Statistical analysis using student's t -test showed that the anti-tumor growth effect of the targeted-IONP-Cisplatin was highly significant compared to no-treatment control ( p <0.005), and significant compared to cisplatin ( p <0.05) and non-targeted IONP-Cisplatin ( p <0.01) treated mouse groups.

Changes in the corticospinal tract We found a significant trend of change along the corticospinal tract only when we used the less stringent threshold of p < 0.005 (uncorrected for multiple comparisons).

The mean right and left carotid intima media thickness in patient and control groups showed a highly significant difference ( p = 0.005 and 0.036 respectively).

86 GO biological process (BP) terms were significantly enriched in the dataset (p-value < 0.05), of which 32 terms were highly significant (p-value < 0.005) ( Figure 3a , Supplementary file 2 ).

Thus, at 12 months of age, paired-pulse ratio was lower in TASTPM than wild type mice at both 25 and 50 ms inter-stimulus intervals ( n = 5–8, two-way ANOVA, main effect of genotype p < 0⋅02), while at 18 months of age, the lower paired-pulse ratio was only evident at 25 ms, resulting in a genotype × interval interaction ( p < 0⋅05) and a highly significant Sidak post hoc pairwise comparison between genotype at 25 ms ( p < 0⋅005). 3.3.2 Inhibitory activity is unchanged Although we have concentrated our detailed analysis on glutamatergic activity, we were able to gain an overview of inhibitory activity from the spontaneous activity recorded in the absence of antagonists by utilising CsCl as the internal patch pipette solution.

Group 1 - Statistically highly significant difference were seen for the values between the two appointments (p = 0.005) for pulse rate with higher values at Appointment 1. - Statistically significant difference were seen for the values between the two appointments (p = 0.041) for respiratory rate with higher values at Appointment 1. 3.3.

Highly significant differences were defined in cases with p -values ≤ 0.005 and significantly different cases with p -values between 0.05 and 0.0051. 5.

Notably, the inhibitory effect of NaAc was highly significant at 42 and 45 dpi ( p < 0.005) ( Figure 7 A).

Additionally, when analyzing each of the temperature indicators and the sum of precipitation for the first 12 days of the pied flycatcher nestling life, we found a statistically significant increase (an increasing trend) for each temperature (year × T mean_12 r = 0.57, p < 0.005; year × T max_12 r = 0.38, p = 0.002; year × T min_12 r = 0.45, p < 0.005), while the decrease for the sum of precipitation showed a decrease in 2015–2019 (year × P 12 r = − 0.44, p < 0.005) (Fig. 3 ).

Grain quality There was a highly significant ( p < 0.005) cultivar × fungicide strategy effect on 100 grain weight ( Table 13 ) and cultivar and treatment effect on SSI ( 1Supplementary Data S3 ).

Conversely in RA this percentage was higher in males than in females in both studies but the difference was highly significant here (p<0.005) but less so in Meyer and colleagues (p = 0.043).

Among them, age (OR: 1.023), previous cardiac surgery (OR: 1.562), pre-operative renal insufficiency (OR: 1.402), and logistic EuroSCORE (OR: 1.014) had a highly significant effect ( p < 0.005).

Only highly significant gene-sets (p < 0.005; FDR < 1%) are shown as nodes in the enrichment map.

4 D renders this relation highly significant ( F (1,42) = 9.14, p = 0.005, ρ 2 = 0.20).

In the ICAN data, Spearman correlational analyses between age and TBR for all permutations showed highly significant correlations (all Cz p < 0.005 unless stated otherwise), as expected, with the strongest correlations for the Session-based averaging method ( r = − 0.28; df = 234) followed by Welch (Hann) ( r = − 0.27; df = 234) and the weakest correlation for Trial based ( r = − 0.26; df = 234).

Further ANOVA analysis ( Table 2 ) performed for all the traits showed highly significant differences in the studied genotypes at P ≤ 0.005.

The analogous analysis for mortality identified RSV as highly significant risk factor (p = 0.005; OR = 4.4), besides age (p = 0.011), sex (p = 0.007), oxygen upon admission (p < 0.001), cough (p = 0.031) and eGFR (p = 0.045), while Influenza A was not (p = 0.861).

Thus, in cohort #1, patients with circadian disruption complained of statistically more severe fatigue ( P < 0.0001), anorexia ( P < 0.0001), and pain ( P < 0.0001), yet only a nonsignificant trend ( P > 0.005) was found for sleep trouble ( P = 0.009).

There was a highly significant difference (p = 0.005) in the mean size of pulmonary infarction in patients with effusion (34.5 cm 3 ) compared to those without it (14.3 cm 3 ), but the size of the effusion had no correlation with the size of pulmonary infarction.

Antibody-positive stained cells were much more abundant in the vitamin D-deficient group when compared to the control group, and the difference was highly significant, especially for PRB ( P < 0.005; Figure 2C and D ).

In contrast to the lack of effect on steady-state levels of PIns, FLUO inhibited the rate of incorporation of 3 H-inositol into PI, PIP and PIP 2 compared with controls; each of these highly significant ( p < 0.005) decreases indicated by the symbol (φ) was directly proportional to the decrease in the steady-state level of inositol (the average decrease in the five components in Figs. 3a, c, d was 45 ± 2%).

As shown in Fig 4A , RGDS-FNIII9/10 coated PLA-nanoparticles bound more or were more endocytosed by HT-1080 than KGES-FNIII9/10 particles (twice) and blank nanocarriers (8 times), but the difference was only highly significant (P<0.005) at the highest concentration (1 million PLA nanoparticles/cell).

2 ) from infected ( n = 4) and non-infected ( n = 8) animals revealed for EAAT2, GluA2, Shank3, and GABA A R α1 a highly significant main effect of infection status ( F 1,10 = 12.93; p = 0.005, two-way repeated measures ANOVA with protein as a within-subject factor and infection status as a between-subject factor) while no significant effect of protein or interaction was observed (all p > 0.804).

We used FLIM-FRET analysis to measure the NDC80 binding in groups of sister kinetochores with similar K-K distances, and observed a highly significant positive correlation (p<0.005) between NDC80 FRET fraction and K-K distance ( Figure 3D ).