Excerpts

Analysis of latency of uncertainty coding In standard uncertainty tasks, each neuron’s smoothed normalized activity aligned at CS onset was further smoothed with a 101 ms causal boxcar kernel and then tested at each millisecond starting 50 ms after CS onset for whether it met the following criteria: (1) highly significant ROC area for distinguishing pooled data from uncertain reward CSs from the certain 0% reward CS (p < 0.005), (2) highly significant ROC area for distinguishing pooled data from uncertain reward CSs from the certain 100% reward CS ( p < 0.005); (3) both ROC areas have the same “sign” (i.e., both > 0.5 indicating activation by uncertainty or < 0.5 indicating inhibition by uncertainty).

No other comparisons approached significance after correction ( p > 0.005; S2 Table ).

In the univariate analysis, an sST2 value>35 ng/mL in STEMI patients showed highly significant predictive power for the risk of events, with an OR of 12.5 (95% CI 2.08-74.81, P =0.005).

The treatment effect on LVM was greater when analysed using the per-protocol population with a highly significant reduction in LVM (change in LVM: metformin group −7.53 ± 4.66 g vs. placebo group −3.13 ± 6.36 g; P = 0.005).

We designed and transfected three ZNF667‐AS1 silencing sequences (Table S1 ) and found that the interference efficiency of si‐ZNF667‐AS1 with siRNA‐1 and siRNA‐3 sequences was significant ( P < 0.05), among which the interference efficiency of siRNA‐1 was highly significant ( P < 0.005), while that of siRNA‐2 was not significant ( P > 0.05; Fig. 2 C,F).

There was a highly significant association between stage of USC and diagnosis of VTE ( p =0.005).

The results for the first cycle are given in Table IV, and it can be seen that the differences beween pretreatment and peak SI were highly significant (P <0.005 for each of the IL-2 con- centrations, Wilcoxon test).

The additional highly significant space-time interaction of zooplankton communities (r 2 = 0.178, p<0.005) suggested that sites behaved differently over time.

The final regression model was highly significant (F [3,52] =4.806, p=0.005), the adjusted R-squared value was 0.172, and each predictor (age, gender, and dose of sodium thiopental) was significant (p=0.05).

The values of F/Wald-statistics are highly significant (p<0.005), which reveal that our models are good-fit.

Of the female subjects, 32.9% exercised regularly and 67.1% irregularly; no between-gender difference was apparent ( P > .005).

From 1979/1991 to 2009, a negative trend was present in expected CIDs over time, which was significant or marginally significant for model A (−0.19 ± 0.06 days/year, p = .005), model B (−0.14 ± 0.07 days/year, p = .07), and CID observations (−0.23 ± 0.13 days/year, p = .11).

Permutation test demonstrated that the relationship between individual plant species and soil topography gradient variables is highly significant ( F = 1.61, p = 0.005; 999 permutations).

In our cohort of 23 nuclear/cytosol fractionated AML patient samples, we observed a highly significant degree of correlation (Spearman Rank R=0.63, P <0.005) between the relative nuclear-localized (as a proportion of total) β-catenin protein and relative nuclear-localized (as a proportion of total) LEF-1 protein ( Figure 5B and C).

Results Multivariable analysis revealed that out of several variables studied six dichotomized features: namely: cigarette smoking, lack of chemotherapy, palliative doses of radiotherapy, high OPN concentration, advanced T stage and high VEGF concentration had a highly significant ( p < 0.005) and independent influence on overall survival in the group of 337 patients.

On the contrary, a CpG methylator phenotype in CRC cells seems to be accompanied by reduced ASS1 production rates as indicated by a highly significant negative correlation with ASS1 level ( p = 0.005, R = −0.68).

For nutrient content in live and dead fine roots, marginally significant or non-significant Genotype × Environment interaction effects were observed for most nutrients, and only one highly significant interaction effect was observed on dead fine root Ca content (p = 0.005) (Table 4 ).

This analysis showed a highly significant correlation ( r = 0.7034; p = 0.005) between both values, suggesting that the potential inhibitory activity of the phenolic compounds over the early stages of adipogenesis in 3T3-L1 adipocytes could be, at least partially, explained by their capacity to interact with the binding pocket of the adipogenesis-mediator PPARγ.

5 A and C ) were related to 1) the relative increase in siRNAs derived from LTR-retrotransposons—notably from Gypsy when comparing the S5 generation to MPV and S1 ( P < 0.01 and P < 0.005, respectively) and 2) the highly significant decrease in other TE-siRNAs in the S1 generation compared with MPV ( P < 0.005 for siRNAs derived from LINEs and P < 0.05 for siRNAs derived from SINEs or class 2 Terminal Inverted Repeats (TIR)-transposons).

Organ meat intake and NASH In univariable and multivariable logistic regression models ( Table 3 ), there was a significant trend (P=0.005) for the association between higher animal organ meat consumption and lower risk of having definite NASH.

By contrast, MUP sharing had a strong and highly significant effect on the likelihood of successful mating ( Table 1 : model 3, p = 0.005; Figure S1 ).

Moreover, the decrease of TH + neurons was highly significant ( p <0.005, compared to DMSO control) but the total number of neurons was not significantly affected compared to DMSO control ( Fig. 5D ), again suggesting an increased sensitivity of DA neurons to Neriifolin.

Conclusions We compared heterozygosity based on fecal- and blood-derived DNA and conclude that there is a highly significant ( p < 0.005) decrease in heterozygosity estimates from fecal samples.

In summary, the data show a highly significant ( p < 0.005) decrease in Chl a growth for both strains in the closed-culture vessels in comparison to the open-culture system at Fe(II) levels representing the Archaean ocean or lower (Fig. 2a, b, e ).

The performance difference in preoperative preparation is at the threshold of significance ( p = 0.005) after Bonferroni correction.