Excerpts

This association was highly significant in patients treated with intensified doses of adalimumab ( β = −0.1474; p = 0.0062) but weak and non-significant in patients treated with non-intensified doses ( β = −0.0193; p = 0.1973) as shown in Figure 3 .

The overall differentiation between the phenotypes was highly significant (L, M1, M2 and M3, H; Fst=0.2335, P=0.0062; Table 3 ), whereas no significant differentiation was detected between any of the pairs of phenotypes (Fst ≥0.0379, P ≥0.1168; Table 3 ).

More participants in Group 1 also disagreed with the statement that their hospital had an effective AMS programme, although this difference did not reach statistical significance (11/57 vs. 1/33; P = 0.0062).

The increase in dorsiflexion was statistically highly significant ( p = 0.0062), as was the increase in palmarflexion ( p < 0.0001).

The results revealed a highly significant association of A 2A R expression with prognosis, only in men; the higher the gene expression, the worse the survival in males ( p value = 0.0062) ( Table 2 ).

We found two highly significant antibody interactions associated with treatment response: anti-CarP with anti-PAD4 ( p = 0.0062), and anti-CCP with RF ( p = 0.00068).

The association between SNP genotype and bolting behavior was tested with a logistic regression model and was mildly significant ( P = 0.0062).

The bsAb’s afucosylation levels exhibited a positive trend with recycled content (p = 0.0062, R 2 = 0.584).

However, this finding of a protecting effect did not reach statistical significance at a bonferroni corrected significance level of p < 0.00625.

lower interference effect) on the Stroop task than those with lower education (although this did not reach statistical significance at p < 0.00625).

A 1-way ANOVA revealed a highly significant overall treatment effect on RGC survival (F(2, 59) = 5.524, P = 0.0063, R 2 = 0.158).

A nearly significant signal was observed in the lysosome gene-set with an OR of 1.17 (p = 0.0063 using GLM; Fig 1 ).

Stimulation of human OVCAR-3 cells revealed highly significant effects of ADAM inhibition on CX3CL1 secretion, as basal values were reduced 3.6-fold by TAPI-2 ( P = 0.0063) and 4-fold by GI254 ( P = 0.0018, Fig. 2 C).

In addition, damaging or rare damaging NOD2 variants were nominally significant across all three burden tests applied (p = 0.0063 to 0.045).

Bacterial metabolites of the quinolinine pathway may interfere with the outcome of infection When assessing virulence of each strain through survival of mice during acute lung infection, we showed a trend toward decreased survival in mice infected with CHA∆kynU strain compared to those infected with CHA∆kynA strain ( p = 0063) (Fig. 7 ).

Extranodal presentation was reported in just over half (50.9%, 54/106) of childhood ML cases and in 20.9% (9/43) of the elderly, which difference was statistically highly significant (P = 0.00635, Chi-square Test) [Table 2 ].

The ASD MCS showed a weakly significant cross-disorder prediction in the SCZ test cohort (cohort 7, P = 6.36 × 10 −3 , AUC = 0.59), but no significance was observed for prediction of the SCZ MCS into the ASD cohorts.

We also observed nominally significant results in relation to SCZ: a positive correlation between SCZ GWAS results and HB scores for complete selection (p = 6.37*10 −3 , S1 Table ; permutation p = 3*10 −3 , S2 Fig ).

There was also a highly significant difference in the distribution of infected and non-infected persons among the five educational levels ( χ 2 4 = 14.3, P = 0.0064; e.g. 86.8% of infected people only went to elementary school, while for non-infected subjects this value was 54.1%).

The statistical analysis confirms this difference is highly significant ( p = 6.4e-3).

There was a statistically significant difference between the two groups for the SOC S score ( p = 0.0113) and the SOC G score ( p = 0.0065) and a trend toward significance for the SCL GSI score ( p = 0.0064), while the differences in the SWE sum score ( p = 0.64) and the FFA G score ( p = 0.42) were not statistically significant.

Moreover, we found that serum HMGB1 concentrations showed a highly significant correlation with SLE disease activity index score (SLEDAI) ( r = 0.4715, P = 0.0064, Figure 1(c) ) and anti-dsDNA antibody levels ( r = 0.6257, P = 0.0001, Figure 1(d) ).

The number of live births per women were significantly higher in women who had CU compared with the subjects having NCU, and their differences were statistically highly significant ( p = 0.0064).

Although the association did not reach statistical significance, the BIN1 variant showed a consistent direction of effect in the AA and HIS subgroups (AA: rs4663105, MAF = 0.41, OR = 1.16, p = 0.0064; HIS: rs4663105, MAF = 0.40, OR = 1.10, p = 0.15).

Motor symptoms showed a marginally significant decrease (p = 0.0064): superficial (p = 0.2285, insignificant) and vibratory sensitivity (p = 0.1095, not significant).