Excerpts

There was an increasing trend of high grade MME ( p = 0.007), IF ( p = 0.03), and TA ( p = 0.039) as the BMI increased.

During the 2007–2016 decade, the overall unadjusted suicide mortality rates showed a significant trend to decline over time ( r = −0.78; p = 0.007) and ranged from 3.1 in 2015 to 4.7 in 2008.

A nominally significant smoking × recent caffeine interaction ( p = 0.007) was observed in non-white participants: recent caffeine intake lengthened RT among past ( p = 0.06) and current ( p = 0.02) smokers but not among never smokers ( p = 0.46) ( Supplementary Table S10 , p = 0.007 for interaction).

Thus, there was a highly significant difference between the asthmatics and controls ( P =0.007).

Meta‐analysis has shown a highly significant relationship ( P = 0.007 OR 1.52) between hospitalization for respiratory syncytial virus (RSV) bronchiolitis and possession of a minor allele for a vitamin D receptor polymorphism (Fok1‐f rs2228570) that lowers transcriptional activity of the vitamin D receptor [ 51 ].

Statistical analysis of the vitality scores further suggested a highly significant group difference ( F = 7.49; p = 0.007), reflecting higher levels of fatigue in MS than Stroke.

This analysis once again revealed a highly significant priming effect overall in the reduced data set ( F (1,12)=10.68, p =0.007) and an insignificant interaction effect between Group and the negative priming effect (although with a higher F -value than that found in the main analysis: F (1,12)=2.66 relative to F (1,30)=0.78).

When adjusting data for predominant motor symptom side, reduced FA persisted in the SN ipsilateral to the more affected body side ( p = 0.034) and a difference in FA in the SN contralateral to the more affected body side came close to being significant ( p = 0.007).

Resolute Integrity, the differences were highly significant ( p = 0.007).

Patients with MAPT mutations showed a trend towards more severe atrophy in left entorhinal cortex (U = 2.0, z = −2.68, p = .007) and fusiform gyrus (U = 1.5, z = −2.72, p = .006) and right perirhinal cortex (U = 1.5, z = −2.67, p = .007) than patients with mutations in the GRN and C9orf72 gene and in right fusiform gyrus compared to bvFTD patients with no gene mutation (U = 13.0, z = −2.80, p = .005). 4 Discussion In this large cohort of bvFTD patients naming problems were a prominent feature of many, although not all, patients (around 50%).

In step 3, the full model was highly significant (adjusted R 2 = 0.353, F = 5.361, P = 0.007).

In diabetic patients (n=17, 21%) the correlations of cfPWV with both fetuin-A and OPG did not reach statistical significance (p=0.173 and p=0.177 respectively) (Figure 2 a and 2 b), while in non-diabetic patients (n=64, 79%) the above correlations were highly significant (p=0.007 and p<0.001 respectively) (Figure 2 c and 2 d).

The increase was + 377% ( P < 0.0001) and + 147% ( P = 0.02) in control and sildenafil rats, respectively, with a highly significant difference between the two groups ( P = 0.007).

Two different doses of galnon (5 mg/kg, n = 9; 10 mg/kg, n = 9) induced robust CPP on the first post-test; saline-injected mice, irrespective of morphine pre-treatment, did not exhibit any preference for the conditioned compartment; this trend was also seen in the lowest dose galnon group (0.5 mg/kg, n = 9), though this effect did not reach statistical significance (treatment: F (4, 39) = 4.118, p = 0.007; test day: F (2, 78) = 5.582, p = 0.007; treatment × test day: F (8, 78) = 2.214, p = 0.035.

A definitive diagnosis was reached in 33/49 malignant, 7/7 intermediate, and 9/10 benign tumors ( P = 0.007 which was highly significant).

To prioritize the study, only those spots with a highly significant ( P < 0.007) difference in expression levels were selected for analysis.

However, the effect of race on valence barely missed significance after adjustment (unadjusted P value=.007; adjusted P value=.08), with white individuals reporting much lower valence scores on average.

The results show that the overall vaccine efficacy by age group interaction was highly significant ( p = 0.007) in the B/T model fit to the outbreak-free data (Additional file 1 : Table S6).

In contrast, regional differences within the AD group showed a trend toward variability, with a significant increase in amyloid β levels in the 10N compared to AmbC (mean difference = 162, p = 0.007).

Consistently, the proliferation of ovarian GC treated with ZEA was highly significant inhibited by Edu staining, which was alleviated by isorhamnetin ( P = 0.007; Fig. 4 F, and G); this beneficial action was abolished by LY294002 (PI3K antagonist) ( Fig. 4 F, and G).

Discarding the eight marginally significant cases, this shows a significantly more frequent prediction of increased damage ( χ 1 2 = 7.35, p = 0.007).

Late 2010/early 2011 inventories and MAR were compared to late 2011 and 2012 inventories and MAR with a student’s T test and differences between the two time periods were highly significant, p = 0.007 for MAR and p = 0.0018 for inventories ( Table 3 ).

Statistical analysis confirmed that the reduction achieved by melanin was highly significant compared with the control (p = 0.007, Student’s t-test).

Following that, the DESTINY-Breast03 ( NCT03529110 ) phase III trial found that T-DXd as a second-line treatment for patients with HER2-positive MBC significantly improved PFS and had a strong trend of OS benefit (HR, 0.55; 95% CI, 0.36 to 0.86; P = 0.007) when compared to T-DM1 (HR, 0.28; 95% CI, 0.22 to 0.37; P < 0.001) [ 14 ].

Results Significantly higher ( U = 253863, p < .001) FMS total scores were found for recruits (mean 15.23 ± SD 2.01 points) when compared to attested officers (14.57 ± 2.96 points) and differences in FMS total scores also approached significance for females (15.24 ± 2.35 points) when compared to males (14.84 ± 2.55 points, U = 186926, p = .007), with age found to be a key, significant factor in explaining these observed differences (F (1,1507) = 23.519, p < .001).