Excerpts

The decrease in NIHSS on day 5 compared to day 1 was highly significant in patients with ischemic stroke (mean change −0.447, P = 0.008) as compared to hemorrhagic stroke (mean change −0.370, P = 0.096).

The p-values of coefficients for these three variables were highly significant (p ≤ 0.008), and thus we presume the regression model to be valid.

Patients with EAD reported more depressive symptoms at endpoint as measured on BDI, though when adjusted for gender this difference only reached borderline significance (p = 0.008).

With a highly significant pathological complete response of 49% (versus 23% in AC patients; p = 0.008) and estimated 5-year survival benefit from combination chemoradiotherapy compared to surgery alone (AC: p = 0.049; SCC: p = 0.011), it is evident that this patient subgroup had a major benefit from this therapeutic intervention [ 10 ].

However, the decrease in the median ratio between 90° abduction to 60° was close to approaching significance ( Z = −2.666, p = 0.008).

Although the decline in total B cells (CD3 − CD19 + CD20 + ) and naïve B cells (CD3 − CD19 + CD20 + CD27 − CD38 lo ) did not reach statistical significance, mature/activated B cells (CD3 − CD19 + CD20 + CD27 + CD38 moderate ) declined significantly from 313 (267–392) cells/10 5 lymphocytes to 64 (28–166), P = 0.008, and memory B cells (CD3 − CD19 + CD20 + CD27 + CD38 − ) decreased from 608 (380–842) cells/10 5 lymphocytes to 101 (36–200), P = 0.004 (Figure 4 ).

The results revealed that treatment of lean adipocytes with 1.0 μM insulin for 1 h stimulated a highly significant (P = 0.008) ~ threefold increase in ADH1B activity compared to untreated control, indicating insulin-induced ADH1B expression results in a proportional increase in activity (Fig. 7 ).

This corresponds to a highly significant dose reduction of 59 % ( p = 0.008) for the maximum heart dose and 75 % ( p = 0.008) for the D 2% of the LAD.

This trend is statistically highly significant (χ 2 = 7.045, p = 0.008) ( Figure 1 ).

A pairwise comparison of PFS between patients with PD-L1 + and PD-L1 − tumors also showed a highly significant difference in PFS outcome ( P = 0.008).

The presence of aggregates at baseline was a highly significant predictor of the clinical response to anti-TNF treatment ( P = 0.008), demonstrating that RA patients with synovial lymphocyte aggregates may have a better response to Infliximab treatment than those with only diffuse leucocyte infiltration [ 59 ].

These associations also persisted and remained highly significant in multivariable-adjusted models for HIV RNA (IRR, 4.05 [95% CI, 1.44-11.36] per IQR; P = .008) and HIV DNA (IRR, 3.35 [95% CI, 1.22-9.19] per IQR; P = .02).

The only marginally significant temporal trend observed was a decrease ( p = 0.008) in POM-C concentrations that occurred between spring and fall during the maize phase of the 3YR rotation, where POM-C fell from a spring high of 2.79 g cm -3 to a fall value of 1.48 g cm -3 ( Fig 1A ).

No significant differences in the mean values of the KTW nor FGG shrinkage% across six time points ( p < 0.05) were observed, whereas highly significant differences in the mean values of GTT across six time points (F = 3.32; p = 0.008) were observed.

Whereas for all mice no associations were observed for microglia activity and behavioral performance, when focusing on only the 12-month-old vaccinated mice and their mock controls, a highly significant correlation was seen between hippocampal microglia activity and AUC of the MWM learning curve ( r = 0.78, p = 0.008), which could completely be attributed to microglia activity in the Hilus ( r = 0.93, p < 0.000).

There was a highly significant (p = 0.008) association between increased survival and the value of the mean score of the 12-chemokine GES.

Patients with PsA showed a highly significant reduction in the frequency of classic plaque ( p = 0.008).

Highly significant simple principal effects of background noise [F (2,36)=4.73, p=0.008] and reverberation [F (2,36)=6.31, p=0.006] were observed.

Here, we found a highly significant effect of reward [ F 1,19 = 8.86, p = 0.008], indicating that subjects were more likely to sustain effort in the late reward period when a high, as compared with a low, reward was at stake (placebo: t 19 = 3.68, p = 0.002; levodopa: t 19 = 2.87, p = 0.010; haloperidol: t 19 = 1.87, p = 0.076).

A correlational analysis between coach rated game intelligence and DF-total correct demonstrated a highly significant and moderate relation between the two factors ( r = 0.37, p = 0.008).

In each case, the ANOVAs showed that the overall models were highly significant ( P < 0.008) indicating significant component effects ( Table 6 ).

A trend toward significance (nominal p -value = 0.008) was also observed in the fifth platform (OAA) ( Figure 5A ).

Strikingly, this neural dissociation between threat levels showed a highly significant relationship to both subjective anxiety reports during the task ( r = .552, p = .008) and trait anxiety ( r = −.503, p = .017) in female participants, but not in male participants ( r = −.082, p = .753 and r = −.290, p = .259, respectively).

A change in the total medical imaging cost for the breast cancer patient claimed every month showed an increasing trend before the amendment (β = 5,475, standard error [SE] = 1,992, P = 0.008) and rapid change immediately after (β = −103,317, SE = 16,152, P < 0.001).

Age was associated with declines in recognition scores [ r = −0.36, t (193) = −5.36, p < 0.0001], and older participants showed a trend toward reduced learning rates [ r = −0.19, t (193) = 3.90, p < 0.008].