A highly significant relationship and a moderate association with anemia (-2.76, CI 95% -9.26 to -0.22; p -value = 0.009) and strong association with very highly significant relationship was noted with COVID-19 (-5.68, CI 95% -6.34 to -0.48; p -value = 0.000) and sun exposure (5.71, CI 95% 0.80 to 0.49; p -value = 0.000).
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However, the presence of a female leader had a strong and highly significant effect on the tendency for males to approach simulated intruders ( B = 4.73, SE = 1.81, z = 2.62, N = 34, P = 0.009; Fig. 1d ).
No significant difference was found for >1.8 s between blue- and red-light stimulus ( t (14) = -1.2, p = 0.125, d = -0.31), but highly significant difference in pupillary change to blue- compared to red-light for <1.7 s ( t (14) = -2.71, p = 0.009, d = -0.70), see Fig 4 .
This endpoint treatment effect was then sustained over time: in follow up intention‐to‐treat (ITT) analysis 6 years after initial treatment end, with 80% of the original cohort assessed at a mean age 10.5 years, the between‐group treatment effect on ADOS scores was preserved (OR −8.2; −1.53, −0.12, p = 0.02), giving a highly significant cumulative effect of therapy (marginal log‐odds effect size of 0.55 [95% CI 0.14–0.91]; p = 0.009; shown as an ‘area between curves’ AUC, Figure 3 ).
Notably, although sex and GCS showed nominally significant interactions ( P = 0.009 and 0.014, respectively), these were not adjusted for multiple comparisons and should be considered hypothesis-generating.
Variation in serological prevalence according to SES and spatial characteristics As substantiated by the highly significant interaction between age and SES ( p = 0.009, Table 3 ), the magnitude of the difference in serological prevalence between the Chiredzi and Hwange SESs varied, particularly as a function of the age class of the animals considered.
In accordance with the in vivo advantage of utilizing an IL-2-independent pathway of costimulation of tumor-specific T cells, in a retrospectively analyzed cohort of patients with metastatic malignant melanoma treated with cyclophosphamide and tumor-antigen transfected DCs ( NCT00978913 ) we observed a highly significant inverse relation between overall survival and expression of IL-2Rα on DC vaccine products (p = 0.009).
In contrast, highly significant negative correlations were seen between the retromolar space area and whole tongue thickness during both respiratory phases (inspiration r = -0.92, p < 0.009; expiration r = −0.96, p < 0.002, Figure 4 ).
Patients with unfavorable outcomes had a significant trend toward higher ESR during treatment compared with patients with favorable outcome ( P = 0.009).
Treatment of animals with Rac1 peptide at all doses failed to influence clinical scores of disease severity or animal weight (data not shown), but animals treated with 2 mg of Rac1 peptide showed a highly significant decrease in paw swelling when compared with treatment with Ctrl peptide (61% reduction, P = 0.009) (Figure 2a, b ).
This finding was statistically highly significant ( p = 0.009).
Post-hoc Wilcoxon signed-rank tests using a Bonferroni corrected alpha of 0.008 revealed a significant difference between children’s spontaneity in the object-centred helping and social-centred comforting tasks ( z = −2.74, p = 0.006) and a marginally significant difference between the social-centred helping and social-centred comforting tasks ( z = −2.60, p = 0.009).
The main statistical analysis showed a highly significant improvement in all experimental group members during the course of treatment as evident from the objective (Wolf Motor Function Test WMFT [ 16 ]: p = 0.009; Frenchay Arm Test FAT [ 17 ]: p = 0.007; Wilcoxon-Rank-Sum-Test) and the subjective (Stroke Impairment Scale SIS [ 18 ]: p = 0.013) scales.
Though the mortality difference was highly significant (absolute risk reduction of 30% for hospital mortality, p = 0.009, NNT = 3.3), only one or two deaths in the hydrocortisone group would have been sufficient to tip the balance toward a non-significant mortality difference and in favor of study continuation, rather than early termination of the trial.
In addition, highly significant interactions influencing C-LDL were also found between ST3GAL4 and ABCA1 , SCARB1 , PLTP , PSKH1 , and NPC1L1 ( p ≤ 0.009–0.001).
We found a highly significant, negative association between log 10 cortisol/DHEA-S ratio and log 10 sCD14 (r = 0.561, p = 0.009).
This analysis showed that, in patients with CHD, the relationship with reduced eGFR was different between people with diabetes and those without, in whom a significant trend of increase in ORs from higher to lower eGFR was observed ( r 2 = 0.92, P = 0.009) ( Figure 1 ).
indirectly conveyed events) showed significant main effects of rotation ( F (1, 29) = 5.16, p = .031, partial η 2 = .15) and experience ( F (1, 29) = 4.51, p = .042, partial η 2 = .13), and a highly significant rotation × experience interaction ( F (1, 29) = 7.83, p = .009, partial η 2 = .21).
This difference is highly significant ( P =0.009).
Resistance was more common among urinary than among fecal strains within each phylogenetic group, the difference being highly significant for groups B2 and D strains ( p = 0.009 and p = 0.003, respectively) and of borderline sig-nificance for groups B1 and A strains ( p = 0.05 for both).
Box's conservative epsilon), the differences in QN IC 50 were highly significant (p < 0.009) at concentrations relevant with AVA plasma concentrations achievable in patients taking 80 mg of AVA daily (Table 1 ).
The correlation of our predicted risk and human cases 14 d later was highly significant ( r = 0.80; n = 8 biweekly accumulations from mid-June through October; p = 0.009).
28.4 in cognitively normal; p = 0.010), with a decreasing trend in overweight/obesity with increasing cognitive impairment ( p = 0.009).
A negative trend was observed for the total sample (-1.3 pp; p = 0.009) and PT (-2.3 pp; p < 0.001), with proportions remaining reduced over time when compared to before the pandemic.
Our meta-regression identified a decreasing trend in SAE RORs with later approval years ( β = −0.027, p = 0.009).