Excerpts

In contrast, we observed significant enrichment for coronary artery disease (CAD) heritability in SGBS D0 (z-score = 2.8, P<2.9x10 -3 ) and adipose tissue (z-score = 3.3, P<5.4x10 -4 ), with weaker and still nominally significant enrichment in D4 (z-score = 2.4, P<9.0x10 -3 ) and D14 (z-score = 2.3, P<0.01); the lack of enrichment in preadipocyte-dependent and adipocyte-dependent peaks may be due to their low genomic coverage.

Behavioral performance Regarding reading comprehension performance, a 2 × 3 mixed ANOVA showed a highly significant main effect of group [ F (1,40) = 7.58, p = 0.009] with a non-significant group by level interaction effect [ F (2,80) = 0.221, p = 0.802].

Follow up univariate tests revealed that differences between healthy and participants with RLBP were highly significant ( P < 0.009) for all the EMG-frequency slope data (raw MFslopes and normalised MFslopes), when controlling for age, weight and MVIC (Table 6 ).

No significant difference could be found on comparing the distraction conditions without belt ( p = 0.240), but a highly significant difference could be observed when comparing the distraction conditions with the belt in compass mode ( p = 0.009).

Strikingly, E-CAD protein expression was a highly significant prognosticator of OC patients at the advanced-stages (III, IV) ( p < 0.009, log-rank ) ( Figure 3 ).

This is driven by a highly significant contribution of parent weight, such that heavier adults have a slower walking cadence than lighter adults (parent weight β = 0.500, t 30 = 2.804, p = 0.009).

After Bonferroni correction, there was a marginally non-significant group difference in visual-motor integration (BEERY VMI; t (21) = 2.86, p = 0.009, d = 0.97).

The genetic correlation was large, highly significant and strongly negative in women ( r G = −0.877, P = 0.009) in a model without covariates, but not in men ( P = 0.777).

The interaction term for this effect was highly significant (p = 0.009).

On the other hand, RSV induced a highly significant rise of TP53 gene expression in FaDu cells, compared to normal HaCaT cells ( p < 0.009, **) and PE/CA-PJ49 tumor cells ( p < 0.05, *) ( Figure 2 A, Table 3 ).

There was a highly significant effect of treatment (Kruskal-Wallis test, χ 2 3 = 11.57, P = 0.009 across all 4 treatment groups), that was dose-related ( r s = -0.773, n = 19, p < 0.001).

Interestingly, there was a highly significant correlation between the expression of ARK5 and SIRT3 ( P = 0.009).

When we performed a paired analysis with the corresponding normal tissues, a highly significant difference in H 2 O 2 production was found in BRAF + TERT ( p = 0.009), BRAF only ( p = 0.003), ALL BRAF ( p < 0.0001), RET or RAS mutated ( p = 0.02), and ALL MUT tumors ( p < 0.0001) but not in non-mutated PTCs ( p = 0.12) ( Figure 2 , panel B). 3.3.

Furthermore, it discriminates with marginal significance (p<0.009 uncorrected) P1b from R2b.

The epithelial MCT1 and stromal MCT4 showed a trend that was negative with all the HP 13 C-MRI metabolic parameters, with a significant negative correlation observed between stromal MCT4 and k PL ( P = 0.009; Fig. 2b , Supplementary Table 3 ).

The overall B/N ratio showed an increasing trend over time ( p = 0.009), and the increase was also most evident in children aged <5 years ( p = 0.020) ( Figure 1B ).

At baseline and 2 weeks, there were no significant differences between DTSQs total scores in the three study arms ( P = 0.283 and P = 0.789) or between the two intervention arms ( P = 0.602 and P = 0.964), but at 16 weeks, the differences were highly significant ( P = 0.009 and P = 0.002).

[ 55 ] reported a highly significant correlation between geographical distance and AFLP-based genetic distance ( r = 0.73, p = 0.009), whereas no correlation could be found between geographical distance and morphological trait-based distance ( r = 0.44, p = 0.07) in their study of 60 breadfruit samples ( Artocarpus altilis ) in India.

With regard to hash smoking, the correlation between patients with STEMI (35, 49.3%) and NSTEMI (8, 22.9%) was highly significant (p=0.009) ( Table 2 ).

Additionally, although not quite statistically significant, the H1c subhaplotype was also associated with a higher risk of CBD (OR = 1.49, 95% CI: 1.11–2.00, P = 0.009).

However, the presence of a female leader had a strong and highly significant effect on the tendency for males to approach simulated intruders ( B = 4.73, SE = 1.81, z = 2.62, N = 34, P = 0.009; Fig. 1d ).

We also assessed eight pancreatic cancer risk loci identified in Chinese and Japanese individuals in our data and noted one nominally significant locus in the combined PanScan and PanC4 results (6p25.3, rs9502893, OR = 0.94, 95% CI 0.92–0.97, P = 0.009: Wald test; Supplementary Table 6 ).

Nowadays, it is perfectly clear that the HLA-DP*03 allele is associated with MS and epitope spreading in MS [ 17 , 22 ], and in this study, we observed the risk susceptibility of this allele in our Hellenic MS sample, at a highly significant level ( p < 0.009, Table 2 ).

In contrast, highly significant negative correlations were seen between the retromolar space area and whole tongue thickness during both respiratory phases (inspiration r = -0.92, p < 0.009; expiration r = −0.96, p < 0.002, Figure 4 ).

A paired t-test showed this reduction was highly significant (p = .009).