Barely Significant

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borderline significantp = 0.0090.2× alphagold
Future perspectives were significantly different between PAC and CG post-intervention (MD [95% CI]: 23.7 [6.2; 41.3], p = 0.004, scale range 0–100) and borderline significant between ExG and CG (MD [95% CI]: 21.8 [4.2; 39.3], p = 0.009, scale range 0–100).
highly significantP = 0.0090.2× alphaqualifiedgold
Treatment of animals with Rac1 peptide at all doses failed to influence clinical scores of disease severity or animal weight (data not shown), but animals treated with 2 mg of Rac1 peptide showed a highly significant decrease in paw swelling when compared with treatment with Ctrl peptide (61% reduction, P = 0.009) (Figure 2a, b ).
highly significantp = 0.0090.2× alphaqualifiedgold
Amino acid (collagen) concentration was surprisingly variable within a single bone, yet when amino acid content was compared with DNA amplification there was a significant difference between successful and failed samples ( p = 0.016), and this difference becomes highly significant ( p = 0.009) if the test compares ‘good’ and ‘failed’ amplifications.
marginally significantp = 0.0090.2× alphagold
Among NHB participants, the interaction remained significant for episodic memory ( β = −0.092, 95% CI = [−0.142, −0.041], p < 0.001, p _FDR = 0.005) and marginally significant for executive function ( β = −0.073, 95% CI = [−0.129, −0.018], p = 0.009, p _FDR = 0.056).
highly significantp = 0.0090.2× alphaqualifiedgold
This endpoint treatment effect was then sustained over time: in follow up intention‐to‐treat (ITT) analysis 6 years after initial treatment end, with 80% of the original cohort assessed at a mean age 10.5 years, the between‐group treatment effect on ADOS scores was preserved (OR −8.2; −1.53, −0.12, p = 0.02), giving a highly significant cumulative effect of therapy (marginal log‐odds effect size of 0.55 [95% CI 0.14–0.91]; p = 0.009; shown as an ‘area between curves’ AUC, Figure 3 ).